Results 301 to 310 of about 349,913 (393)

Natural variation of an E3 ubiquitin ligase encoding gene Chalk9 regulates grain chalkiness in rice. [PDF]

Nat Commun
Hu Z, Liu H, Guo M, Han X, Li Y, Chen R, Guo Y, Yang Y, Sun S, Zhou Y, Gu M, Yan C.   +11 more
europepmc   +1 more source

WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism [PDF]

, 2020
Abe, T., Furuya, K., Higami, Y., Hoshino, S., Kawabe, H., Kobayashi, M., Konno, R., Miura, K., Mizunoe, Y., Nakagawa, Y., Nakamura, T., Okita, N., Sudo, Y., Tagawa, R., Wakasawa, H.   +14 more
core   +1 more source

X‐ray controlled release strategy in cancer therapy

BMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan, Hongxiang Huang, Huihui Liu, Jinglang Gong, Changjun Li, Xiaolian Sun   +5 more
wiley   +1 more source

MKLN1-dependent GID4/CTLH E3 ubiquitin ligase complex assemblies are required to support B-cell antibody diversification. [PDF]

J Immunol
Barbulescu P, Wong MK, Baronian L, Wang P, Aderinto A, Kneussel M, Martin A.   +6 more
europepmc   +1 more source

High-throughput screening of E3 ubiquitin ligases identifies TRIM48 as a novel negative regulator of RIG-I signaling

Guandi Wu, Jamie Frankish, Joschka Willemsen, Dominik Ricken, Jonas P. Becker, Darius Schweinoch, Jürgen Beneke, Sandra Wüst, Nina Beil, Petr Matula, Karl Rohr, Holger Erfle, Lars Kaderali, Marco Binder   +13 more
openalex   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Antioxidant Activity and Potential Cholesterol Modulating Effect of Punica granatum L. Peel Hydroethanolic Extract

Chemistry &Biodiversity, EarlyView.
Punica granatum peel extract is rich in phenolic compounds, exhibits strong antioxidant activity, and modulates the expression of PCSK9 and LDL receptors. Collectively, these findings suggest a potential cardioprotective effect of the extract. ABSTRACT Lipoprotein metabolism is regulated by several key proteins, notably proprotein convertase subtilisin/
Raja Chaaba, Amel Nakbi, Ilaria Rossi, Hanen Jrah, Zahra Amri, Nicola Ferri, Sonia Hammami, Stefano Dall'Acqua, Mohamed Hammami, Sounira Mehri   +9 more
wiley   +1 more source

TIPE2 Protects Bronchial Epithelial Cells From Pyroptosis and Oxidative Stress by Interacting With the E3 Ubiquitin Ligase FBW1A in Asthmatic Mice. [PDF]

J Biochem Mol Toxicol
Li W, Zhang Y, Wu Y, Wang D, Ge J, Zhao H, Liu Y.   +6 more
europepmc   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, EarlyView.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

The Ac/N-Degron Domain of MARCHF6 E3 Ubiquitin Ligase and Its Role in Regulating Ferroptosis. [PDF]

Cells
Omoniyi H, Hohman G, Eldeeb M.
europepmc   +1 more source