Results 301 to 310 of about 327,531 (416)

Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond

Macromolecular Bioscience, EarlyView.
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley   +1 more source

E3 ubiquitin ligase TRIM2 identified as a novel suppressor of CYP11B2 and aldosterone production. [PDF]

Cell Mol Life Sci
Chen L, Hu X, Wang G, Yu F, Dai Z, Jian X, Li Y, Xiang W, Meng Z.   +8 more
europepmc   +1 more source

A Molecular Basis for Stabilization of the von Hippel-Lindau (VHL) Tumor Suppressor Protein by Components of the VHL Ubiquitin Ligase [PDF]

, 2002
Takumi Kamura, Christopher S. Brower, Ronald Conaway, Joan Conaway   +3 more
openalex   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Differences in structure, dynamics, and zinc coordination between isoforms of human ubiquitin ligase UBE3A. [PDF]

J Biol Chem
Bregnard TA, Fairchild D, Chen X, Erlandsen H, Tarasov SG, Walters KJ, Korzhnev DM, Bezsonova I.   +7 more
europepmc   +1 more source

In Vivo Action of the HRD Ubiquitin Ligase Complex: Mechanisms of Endoplasmic Reticulum Quality Control and Sterol Regulation

, 2001
Richard G. Gardner, Alexander G. Shearer, Randolph Y. Hampton   +2 more
openalex   +1 more source

Transferable Domain in the G₁ Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCF^Cdc4 to SCF^Grr1 [PDF]

, 2002
Catherine Berset, Peter Griač, Rebecca Tempel, Janna La Rue, Curt Wittenberg, Stefan Lanker   +5 more
openalex   +1 more source

Myoclonic Dystonia: A Common Phenomenology in the Pleomorphic Movements of Angelman Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Angelman syndrome (AS) is a neurodevelopmental disorder characterized by developmental delay, intellectual disability, a sociable demeanor, and abnormal movements. People with AS often exhibit multiple types of abnormal movements, including nonepileptic myoclonus, tremor, and dystonia, which hamper attempts to identify phenomenology
Robert P. Carson, Heather Riordan, Brittany Short, Thomas Davis, John Fang, Andrew Giritharan, David A. Isaacs, Joanna Blackburn, Bhooma Aravamuthan   +8 more
wiley   +1 more source

UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation. [PDF]

Nucleic Acids Res
Tiedemann RL, Hrit J, Du Q, Wiseman AK, Eden HE, Dickson BM, Kong X, Chomiak AA, Vaughan RM, Tibben BM, Hebert JM, David Y, Zhou W, Baylin SB, Jones PA, Clark SJ, Rothbart SB.   +16 more
europepmc   +1 more source

Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p. [PDF]

, 2002
Volker Seibert, Corinna Prohl, Ida Schoultz, Edward K. Rhee, Rebecca Lopez, Kareem Abderazzaq, Chunshui Zhou, Dieter A Wolf   +7 more
openalex   +1 more source