Results 311 to 320 of about 327,531 (416)

The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis. [PDF]

PLoS Genet
Li Q, Lim KY, Altawell R, Verderose F, Li X, Dong W, Martinez J, Dickman D, Stavropoulos N.   +8 more
europepmc   +1 more source

The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis

Nature Communications, 2014
P. Xie, Minghua Zhang, Shan He, Kefeng Lu, Yuhan Chen, G. Xing, Yiming Lu, Ping Liu, Yang Li, Shaoxia Wang, N. Chai, Jiawei Wu, Haiteng Deng, Hong-Rui Wang, Yu Cao, Fei Zhao, Yu Cui, Jian Wang, F. He, Lingqiang Zhang   +19 more
semanticscholar   +1 more source

Leucine Supplementation Counteracts the Atrophic Effects of HDAC4 in Rat Skeletal Muscle Submitted to Hindlimb Immobilization

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims We previously demonstrated that leucine supplementation significantly reduces histone deacetylase 4 (HDAC4) expression induced by hindlimb immobilization, thereby attenuating the increase in HDAC4 protein levels and nuclear accumulation.
Paula K. N. Alves, André Cruz, William J. Silva, Afonso M. Melazzo, Siegfried Labeit, Volker Adams, Anselmo S. Moriscot   +6 more
wiley   +1 more source

Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms. [PDF]

J Biol Chem
Chung DH, Connelly EJ, Unnikrishnan A, Chuo SW, Wucherer K, Nadel CM, Gestwicki JE, Southworth DR, Craik CS.   +8 more
europepmc   +1 more source

Targeted Degradation of Abscisic Acid Receptors Is Mediated by the Ubiquitin Ligase Substrate Adaptor DDA1 in Arabidopsis[W]

The Plant Cell, 2014
M. L. Irigoyen, Elisa Iniesto, Lesia Rodriguez, María Isabel Puga, Y. Yanagawa, E. Pick, E. Strickland, J. Paz-Ares, N. Wei, G. De Jaeger, P. L. Rodriguez, X. Deng, V. Rubio   +12 more
semanticscholar   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Correction: E3 Ubiquitin Ligase OsRFI2 Regulates Salinity Tolerance by Targeting Ascorbate Peroxidase OsAPX8 for its Degradation in Rice. [PDF]

Rice (N Y)
Zhao W, Wen J, Zhao J, Liu L, Wang M, Huang M, Fang C, Liu Q.   +7 more
europepmc   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4. [PDF]

mBio
Vats A, Braga L, Kavcic N, Massimi P, Schneider E, Giacca M, Laimins LA, Banks L.   +7 more
europepmc   +1 more source

Comparing Venous vs. Capillary Blood Collection Methods for Proteomic Measurement in Peripheral Blood

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Background Capillary blood collection has a number of advantages over venous collection, especially in the context of increasing decentralized clinical trials and field‐based testing. No studies are available comparing venous versus capillary blood collection for proteomics measurement.
Mary Ni Lochlainn, Nathan J. Cheetham, Mario Falchi, Paolo Piazza, Claire J. Steves   +4 more
wiley   +1 more source