Results 351 to 360 of about 327,531 (416)

PPTC7 acts as an essential co-factor of the SCF^FBXL4 ubiquitin ligase complex to restrict BNIP3/3L-dependent mitophagy. [PDF]

Cell Death Dis
Xu X, Chen Y, Fei S, Jiang X, Zhou X, Xue Y, Li Y, Zhao SM, Huang Y, Wang C.   +9 more
europepmc   +1 more source

At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic (BI01) Administration on DNA Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle

Aging Cell, EarlyView.
Injury then recovery markedly rewires the DNA methylome in aged skeletal muscle.The addition of senolytics during muscle regeneration decelerates DNAmAGE more than regeneration alone as well as targets collagen remodeling and stem cell function‐related genes.
Toby L. Chambers, Jaden Wells, Pieter Jan Koopmans, Francielly Morena, Zain B. Malik, Nicholas P. Greene, Antonio Filareto, Michael Franti, Patrizia Sini, Harald Weinstabl, Robert T. Brooke, Milda Milčiūtė, Juozas Gordevičius, Steve Horvath, Yuan Wen, Cory M. Dungan, Kevin A. Murach   +16 more
wiley   +1 more source

Systematic Analysis of Cotton RING E3 Ubiquitin Ligase Genes Reveals Their Potential Involvement in Salt Stress Tolerance. [PDF]

Int J Mol Sci
Li H, Chen Y, Fu M, Wang L, Liu R, Liu Z.   +5 more
europepmc   +1 more source

Investigating protein degradability through site-specific ubiquitin ligase recruitment. [PDF]

RSC Chem Biol
Shade O, Ryan A, Belsito G, Deiters A.
europepmc   +1 more source

Echinococcus granulosus antigen B regulates T‐cell function through inhibition of signal transducer and activator of transcription 3 in experimental immune thrombocytopenia

British Journal of Haematology, EarlyView.
During the pathological process of immune thrombocytopenia, signal transducer and activator of transcription 3 (STAT3) is activated by JAKs, leading to the production of a large number of inflammatory cytokines and promoting the activation of Th1, Th2 and Th17 cells.
Yingbin Yue, Yunfei Zhang, Yongfeng Cheng, Hongjie Jiao, Mei Yan   +4 more
wiley   +1 more source

TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε

Fujisawa R, Labib KP.
europepmc   +1 more source

Ubiquitin Ligase U-Box51 Positively Regulates Drought Stress in Potato (Solanum tuberosum L.). [PDF]

Int J Mol Sci
Wei M, Ghimire S, Rijal A, Wang K, Zhang H, Si H, Tang X.   +6 more
europepmc   +1 more source

The molecular landscape of AL amyloidosis

British Journal of Haematology, EarlyView.
Within the bone marrow, the clonal plasma cell population exhibits an abnormal expression of non‐coding RNAs, which, in turn, upregulates anti‐apoptotic genes (BCL2, MCL1, BCL2L1), leading to an anti‐apoptotic effect that promotes plasma cell survival.
Tal Zvida‐Bloch, Eli Muchtar, Angela Dispenzieri, Ofer Shpilberg, Oshrat Hershkovitz‐Rokah   +4 more
wiley   +1 more source

Itchy E3 Ubiquitin Ligase-Mediated Ubiquitination of Ferritin Light Chain Contributes to Endothelial Ferroptosis in Atherosclerosis. [PDF]

Int J Mol Sci
Zeng Y, Fu S, Xia Y, Meng G, Xu X.
europepmc   +1 more source

The hGID^GID4 E3 ubiquitin ligase complex targets ARHGAP11A to regulate cell migration. [PDF]

Life Sci Alliance
Bagci H, Winkler M, Grädel B, Uliana F, Boulais J, Mohamed WI, Park SL, Côté JF, Pertz O, Peter M.   +9 more
europepmc   +1 more source