Results 231 to 240 of about 33,702 (335)

RING E3 ligases:key regulatory elements are involved in abiotic stress responses in plants [PDF]

, 2017
Cho, Seok Keun, Hong, Jeong Soo, Kim, Jong Hum, Kim, Woo Taek, Oh, Tae Rin, Ryu, Moon Young, Yang, Seong Wook   +6 more
core   +1 more source

Cancer Specific CAIX‐Targeting Supramolecular Lysosome‐Targeting Chimeras (Supra‐LYTAC) for Targeted Protein Degradation

Advanced Science, EarlyView.
Spatiotemporal Supra‐LYTAC formation near cancerous membrane via CAIX‐targeting is achieved. As a result of generation of Supra‐LYTAC, POI trafficking into lysosome is significantly implemented for targeted protein degradation. Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable ...
Dohyun Kim, Gyeongseok Yang, Chaelyeong Lim, Gaeun Park, Jaemo Lee, Youjung Sim, Ja‐Hyoung Ryu   +6 more
wiley   +1 more source

Legionella pneumophila evades host-autophagic clearance using phosphoribosyl-polyubiquitin chains. [PDF]

Nat Commun
Choi M, Jeong M, Kang S, Jeon H, Shin D.
europepmc   +1 more source

Auto-ubiquitination of ubiquitin-activating enzymes from chicken breast muscle [PDF]

, 1990
J.E. Arnold, Wieland Gevers
openalex   +1 more source

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

The Multifaceted Ubiquitination of BIK1 During Plant Immunity in Arabidopsis thaliana. [PDF]

Int J Mol Sci
Fu J, Wang H, Chen Y, Zhang C, Zou Y.
europepmc   +1 more source

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source

A human ubiquitin carboxyl extension protein functions in yeast.

, 1990
Brett P. Monia, David J. Ecker, Daniel Finley, Stanley T. Crooke   +3 more
openalex   +1 more source

Ubiquitin Immunostaining of Concentric Lamellar Bodies in Axon Terminals and Preterminal Axons in Cerebellar and Vestibular Nuclei of Groggy Mutant Rat

, 1994
Ikuo Takeuchi, Yoshiko Takeuchi, Eiko Aoki   +2 more
openalex   +2 more sources

Purification and characterization of a ubiquitin carrier protein kinase from HeLa cells. [PDF]

, 1994
S. K. Kong, P Boon Chock
openalex   +1 more source