Results 251 to 260 of about 33,989 (317)

Distinct proteomic profiles of plasma-derived extracellular vesicles in healthy, benign, and triple-negative breast cancer: candidate biomarkers for liquid biopsy. [PDF]

Sci Rep
Tamarindo GH, Novais AA, Frigieri BM, Alves DL, de Souza CA, Amadeu A, da Silveira JC, Souza FF, Bordin NA, Chuffa LGA, Zuccari DAPC.   +10 more
europepmc   +1 more source

Tumour Necrosis Factor Enhances induction by beta-Interferon of a Ubiquitin Cross-reactive Protein

, 1990
Patricia Buckley Ahrens, Françoise Besançon, Sylvie Mémet, Helmut Ankel   +3 more
openalex   +1 more source

SNORA74A Drives Self‐Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling

Advanced Science, EarlyView.
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou, Yang Gu, Zhibin Yi, Jianyi Wang, Zhen Xiong, Hui Guo, Ying Du, Xiaoxiao Zhu, Lei He, Weizheng Ren, Yong Tian, Yanying Wang, Zusen Fan   +12 more
wiley   +1 more source

Antagonistic Ghd7‐OsNAC42 Complexes Modulate Carbon and Nitrogen Metabolism to Achieves Superior Quality and High Yield in Rice

Advanced Science, EarlyView.
The complex centered on Ghd7 binds to numerous carbon and nitrogen metabolism genes on the genome through the corresponding motifs and transactivates the transcriptional expression of these carbon and nitrogen metabolism genes. With the assistance of OsNAC42 and other unknown Ghd7‐interacting proteins, this complex can regulate different metabolic ...
Guangming Lou, Pingli Chen, Pingbo Li, Haozhou Gao, Jiawang Xiong, Shanshan Wan, Yuanyuan Zheng, Yufu Wang, Mufid Alam, Yingnanjun Chen, Lei Wang, Jingjing Bai, Xuan Tan, Wenting Rao, Bian Wu, Hao Zhou, Yanhua Li, Guanjun Gao, Qinglu Zhang, Jinghua Xiao, Xianghua Li, Xuelei lai, Qifa Zhang, Yuqing He   +23 more
wiley   +1 more source

α-Synuclein ubiquitination - functions in proteostasis and development of Lewy bodies. [PDF]

Front Mol Neurosci
Ho HH, Wing SS.
europepmc   +1 more source

Heterogeneity in the structure of the ubiquitin conjugates of human alpha globin.

, 1994
Joseph R. Shaeffer
openalex   +1 more source

Ezetimibe Engineered L14‐8 Suppresses Advanced Prostate Cancer by Activating PLK1/TP53‐SAT1‐Induced Ferroptosis

Advanced Science, EarlyView.
L14‐8, a small molecule derived from the marketed drug ezetimibe, potently inhibits advanced prostate cancer independent of androgen receptor signaling. L14‐8 binds PLK1, triggering its ubiquitin‐mediated degradation. This activates TP53‐dependent transcription of SAT1, inducing ferroptosis and suppressing tumor growth in prostate cancer patient ...
Yu Zhang, Xiao‐wen Song, Na Zhang, Xue‐hui Li, Fan‐chen Wu, Yu‐ang Wei, Dong‐liang Xu, Ling‐fan Xu, Fu‐wen Yuan   +8 more
wiley   +1 more source

Ubiquitous regulation of cerebrovascular diseases by ubiquitin-modifying enzymes. [PDF]

Clin Transl Med
Huang J, Zhu Z, Schlüter D, Lambertsen KL, Song W, Wang X.   +5 more
europepmc   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source