Results 261 to 270 of about 115,936 (355)

Ubiquitin [PDF]

, 2018
openaire   +1 more source

SNORA74A Drives Self‐Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling

Advanced Science, EarlyView.
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou, Yang Gu, Zhibin Yi, Jianyi Wang, Zhen Xiong, Hui Guo, Ying Du, Xiaoxiao Zhu, Lei He, Weizheng Ren, Yong Tian, Yanying Wang, Zusen Fan   +12 more
wiley   +1 more source

Impaired K48-polyubiquitination downmodulates mouse norovirus propagation. [PDF]

Front Cell Infect Microbiol
Wakeford E, Werkmeister E, Cayet D, Poiret S, Daniel C, Mackenzie J, Sirard JC, Lafont F, Muharram G.   +8 more
europepmc   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

Tumour Necrosis Factor Enhances induction by beta-Interferon of a Ubiquitin Cross-reactive Protein

, 1990
Patricia Buckley Ahrens, Françoise Besançon, Sylvie Mémet, Helmut Ankel   +3 more
openalex   +1 more source

Insights into the fungal secretomes and their roles in the formation and stabilization of the biogenic silver nanoparticles. [PDF]

RSC Adv
Santana da Costa T, Delgado GG, Braga CB, Tasic L.   +3 more
europepmc   +1 more source

MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition

Advanced Science, EarlyView.
Under cold stress, MdDSK2a‐like is degraded via the 26S proteasome pathway, thereby alleviating the degradation of MdMTA induced by the 26S proteasome and autophagy pathways mediated by MdDSK2a‐like. The accumulated MdMTA increases the m6A levels of cold‐responsive genes, thereby contributing to increased ROS detoxification, deposition of cell wall, as
Nan Hou, Jieqiang He, Chana Bao, Fang Zhi, Xiaoxia Shen, Yu Liu, Chaoshuo Li, Tianle Fan, Xinyue Yang, Baohua Chu, Gege Qin, Zeyuan Liu, Chuang Mei, Bin Tan, Jiancan Feng, Fengwang Ma, Mickael Malnoy, Xuewei Li, Qingmei Guan   +18 more
wiley   +1 more source

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo

EMBO Reports, 2014
H. Vlaming, T. Welsem, E. L. Graaf, David Ontoso, A. Altelaar, Pedro A. San-Segundo, A. Heck, F. Leeuwen   +7 more
semanticscholar   +1 more source

p.Phe508del-CFTR Trafficking: A Protein Quality Control Perspective Through UPR, UPS, and Autophagy. [PDF]

Int J Mol Sci
Trouvé P, Férec C.
europepmc   +1 more source

Single‐Cell Transcriptome Reveals Aquaporin‐Mediated Carbon Nanosol‐Induced Growth Promotion of Plants

Advanced Science, EarlyView.
Carbon nanosol (CNS) exhibits rapid root penetration capacity, enhancing plant growth through boosting stomatal density and antioxidative enzyme activity. Single‐cell transcriptomic profiling uncovers cell type‐specific gene expression patterns and developmental trajectories during CNS‐mediated growth promotion.
Lingtong Cheng, Zechao Qu, Qiansi Chen, Lin Wang, Huan Su, Jiemeng Tao, Peng Lu, Taibo Liang, Jianfeng Zhang, Peijian Cao, Jingjing Jin   +10 more
wiley   +1 more source