Results 71 to 80 of about 16,509 (208)

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang   +4 more
wiley   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, Volume 117, Issue 3, Page 642-652, September 2026.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

AVALIAÇÃO DE PERFIL EMPREENDEDOR EM MEIO ACADÊMICO

open access: yesRevista Gestão e Desenvolvimento, 2018
Este estudo teve o intuito de identificar quais características empreendedoras podem ser encontradas nos alunos formandos do curso de Comércio Internacional de uma universidade localizada na serra gaúcha. A identificação de tais atributos poderá auxiliar
Renata Muraro   +4 more
doaj   +1 more source

Toward Enhanced Inertial Sensing via Dynamically Soft Topological States in Piezoelectric Microacoustic Metamaterials

open access: yesAdvanced Functional Materials, Volume 36, Issue 62, 3 August 2026.
A piezoelectric microacoustic wave device exploiting topologically protected interface states with significantly higher dynamic compliance than Lamb or Rayleigh modes achieves record‐high out‐of‐plane particle velocities exceeding 51 m/s. These findings indicate that leveraging topological interface states can overcome key limitations of piezoelectric ...
Onurcan Kaya   +12 more
wiley   +1 more source

O crescimento econômico e as consequências das externalidades ambientais negativas decorrentes do processo produtivo

open access: yesRevista de Direito Econômico e Socioambiental, 2011
A humanidade não mais convive em harmonia com os recursos naturais que, assim como a economia, são importantes para a sociedade. Considerando a preocupação com a qualidade de vida, verifica-se que o desenvolvimento econômico deve ocorrer de forma ...
Liane Pioner Sartori, Lilian Gewehr
doaj   +1 more source

UC: a language for the connection machine

open access: yesProceedings SUPERCOMPUTING '90, 2002
n designing parallel languages, the concern for defining a simple virtual machine must be balanced against the need to efficiently map a program on a specific architecture. UC addresses this problem by separating the programming task from efficiency considerations.
Bagrodia, R., Chandy, K. M., Kwan, E.
openaire   +2 more sources

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

Reorganizing the layout as a production optimization strategy

open access: yesGEPROS: Gestão da Produção, Operações e Sistemas, 2014
Organizations are embedded in competitive environments that require the improvement of manufacturing practices, highlighting the physical arrangement as a major challenge in industrial management.
Gilson Pires da Rosa   +3 more
doaj  

Comprehensive Pan‐Cancer Analysis of ABCA1: Insights From Multi‐Omics Data and Exploratory Validation in Esophageal Squamous Cell Carcinoma

open access: yesCell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Cancer remains a major cause of global mortality, necessitating the identification of novel biomarkers to improve prognosis and guide therapy. ABCA1, an ATP‐binding cassette transporter involved in cholesterol efflux, has been implicated in tumorigenesis, yet its pan‐cancer roles and clinical relevance are not fully understood.
Chenyang Wang   +16 more
wiley   +1 more source

National and Individual‐Level Economic Burden of Local Corticosteroid Use and Concomitant Use of Multiple Local Corticosteroid Formulations—A Nationwide Cohort Study

open access: yes
Clinical &Experimental Allergy, EarlyView.
Kjell Erik Julius Håkansson   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy