Results 81 to 90 of about 16,509 (208)

TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang   +8 more
wiley   +1 more source

COMPORTAMENTO HIDROGEOLÓGICO DE POÇOS TUBULARES ASSOCIADOS ÀS ESTRUTURAS PRIMÁRIAS DAS ROCHAS VULCÂNICAS DA FORMAÇÃO SERRA GERAL

open access: yesRevista Águas Subterrâneas, 2007
Este trabalho tem por objetivo apresentar dados sobre o comportamento hidrogeológico de poços tubulares associados às estruturas primárias das rochas vulcânicas da Formação Serra Geral, na região nordeste do Estado do RS.
Pedro Antonio Roehe Reginato   +2 more
doaj  

A molecular landscape and prognosis signature based on histone tyrosine sulfation in pan‐cancer analysis

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
A pan‐cancer transcriptional signature based on histone tyrosine sulfation (HYsulf) reveals associations with immune infiltration, metabolic reprogramming and patient prognosis, thereby enabling the development of predictive nomograms for PCPG and UVM.
Meijuan Cai   +7 more
wiley   +1 more source

Corticosteroid Exposure in Chronic Rhinosinusitis and Global Airway Disease: Adrenal and Bone Impact

open access: yesThe Laryngoscope, Volume 136, Issue 8, Page 3398-3409, August 2026.
ABSTRACT Objective To investigate cumulative corticosteroid (CC) burden in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), with or without coexisting asthma (global airway disease, GAD), referred for biologic treatment, and to assess the prevalence of CC‐related comorbidities, including secondary adrenal insufficiency, osteopenia and ...
Christiane Haase   +7 more
wiley   +1 more source

Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 8, August 2026.
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng   +9 more
wiley   +1 more source

Enhancing Rock Strength Prediction and Features Selection by Coupling Well Log Data and Deep Learning Approaches in Reservoir Geomechanics

open access: yesInternational Journal for Numerical and Analytical Methods in Geomechanics, Volume 50, Issue 11, Page 4724-4738, 10 August 2026.
ABSTRACT Accurate rock strength parameters play a vital role in petroleum and mining operations for sustainable drilling activities, and wellbore stability analysis. This study investigates the applicability of deep learning techniques for assessing data‐driven models, and to conduct parametric sensitivity examination for feature attributes ranking to ...
Mohammad Islam Miah   +2 more
wiley   +1 more source

Umbilical Cord: A Non‐Invasive DNA Source for Sea Turtle Genomics

open access: yesMolecular Ecology Resources, Volume 26, Issue 6, August 2026.
ABSTRACT High‐throughput sequencing has revolutionised conservation genomics by enabling genome‐wide information even in non‐model species. However, obtaining non‐invasive samples for genomics remains challenging in species like sea turtles, which spend most of their lives in the open ocean.
Gisela Marín‐Capuz   +4 more
wiley   +1 more source

Inovação de marketing em Instituições de Ensino Superior da Serra Gaúcha

open access: yesRevista Gestão Universitária na América Latina, 2013
http://dx.doi.org/10.5007/1983-4535.2013v6n2p79 Na perspectiva do contexto econômico das organizações, a inovação tem sido alvo de estudo de acadêmicos e empresários, pois apresenta a capacidade de transformar economicamente a situação de uma ...
Julio Cesar Ferro de Guimarães   +4 more
doaj  

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

open access: yesHistopathology, Volume 89, Issue 2, Page 240-250, August 2026.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao   +11 more
wiley   +1 more source

The Effect of Periwinkle Shell Ash (PSA) on Geotechnical Properties of Lateritic Soil for Road Construction Application

open access: yesPlatform, a Journal of Engineering
The study explores the enhancement of geotechnical characteristics of lateritic soil sourced from a popular burrow pit site in Kano State, Nigeria, by incorporating Periwinkle Shell Ash (PSA). The soil sample was mixed with 0 to 10% PSA content at 2%
Salisu Yusuf   +4 more
doaj  

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