Results 61 to 70 of about 5,986 (191)

PREVALENCE AND RISK FACTORS OF CYTOMEGALOVIRUS INFECTION AMONG HAEMODIALYSIS PATIENTS IN SOUTHERN GAZA STRIP, PALESTINE

Global Journal of Public Health Medicine, 2021
Introduction: End-Stage Renal Disease patients (ESRD) on maintenance Haemodialysis (HD) are at high risk of acquiring Cytomegalovirus (CMV). The aim of the study was to determine the prevalence and risk factors of CMV infection among HD patients from ...
Abed El Kader Y. Elottol, Akram Altaher, Asma R. Al-saqqa, Ghadeer S. Abu Teba, Amany S. Al-Jamal, Nozha S. Abu Taha   +5 more
doaj   +1 more source

Kosmotropes and chaotropes: modelling preferential exclusion, binding and aggregate stability [PDF]

, 2004
Kosmotropic cosolvents added to an aqueous solution promote the aggregation of hydrophobic solute particles, while chaotropic cosolvents act to destabilise such aggregates. We discuss the mechanism for these phenomena within an adapted version of the two-
Moelbert, Susanne, Normand, B., Rios, Paolo De Los   +2 more
core   +1 more source

Unimolecular branched block copolymer nanoparticles in methanol for the preparation of poorly water-soluble drug nanoparticles [PDF]

, 2017
Unimolecular branched polymer nanoparticles are formed in methanol via a simple thermal annealing process, which can be used to produce aqueous drug nanoparticle suspensions.
He, Tao, Jackson, Alexander W, Liu, Jian-Hua, Wais, Ulrike, Wang, Yan-Hong, Xiang, Yu, Zhang, Haifei, Zuo, Yan-Ming   +7 more
core   +1 more source

Phasentrennung von Nukleinsäuren: Mechanismen, Eigenschaften und Anwendungen

Angewandte Chemie, EarlyView.
Jüngste Entdeckungen zeigen, dass einzelsträngige langkettige Nukleinsäuren temperaturinduziert phasentrennen und dabei mikrometergroße Kondensate bilden. Dieser Minireview fasst das aktuelle mechanistische Verständnis dieses Phänomens zusammen, beschreibt Strategien zur gezielten Kontrolle der physikalischen und chemischen Eigenschaften der Kondensate
Weixiang Chen, Johann Fritzen, Andreas Walther   +2 more
wiley   +1 more source

Effect of Cation Structure in Quinolinium-Based Ionic Liquids on the Solubility in Aromatic Sulfur Compounds or Heptane: Thermodynamic Study on Phase Diagrams

Molecules, 2020
Experimental and theoretical studies on thermodynamic properties of quinolinium-based ionic liquids (ILs) based on bis(trifluoromethylsulfonyl)imide anion (namely N-butyl-quinoloinium bis(trifluoromethylsulfonyl)imide, [BQuin][NTf2], N-hexylquinoloinium ...
Marta Królikowska, Marek Królikowski, Urszula Domańska   +2 more
doaj   +1 more source

On the Molecular Origin of the Cooperative Coil-to-globule Transition of Poly(N-isopropylacrylamide) in Water

, 2018
By means of atomistic molecular dynamics simulations we investigate the behaviour of poly(N-isopropylacrylamide), PNIPAM, in water at temperatures below and above the lower critical solution temperature (LCST), including the undercooled regime.
Chiessi, E., Tavagnacco, L., Zaccarelli, E.   +2 more
core   +1 more source

Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications

Angewandte Chemie International Edition, EarlyView.
Recent discoveries have shown that single‐stranded long‐chain nucleic acids can undergo temperature‐induced phase separation, enabling formation of micrometer‐sized condensates. This Minireview discusses the current mechanistic understanding of this phenomenon, highlights strategies for controlling the physical and chemical properties of these ...
Weixiang Chen, Johann Fritzen, Andreas Walther   +2 more
wiley   +1 more source

Upper-critical solution temperature (UCST) polymer functionalized nanomedicine for controlled drug release and hypoxia alleviation in hepatocellular carcinoma therapy.

PLoS ONE, 2023
Recently, bioinspired material such as nanoparticle has been successfully applied in the cancer therapy. However, how to precisely control the drug release from nanomedicine in tumor tissue and overcome the hypoxic microenvironment of tumor tissue is ...
Xiaoya Niu, Yi Fu, Lei Feng, Maodi Xie, Bei Li, Lin Que, Zhen You   +6 more
doaj   +1 more source

Upper-Critical-Solution-Temperature Polymer Modified Gold Nanorods for Laser Controlled Drug Release and Enhanced Anti-Tumour Therapy

Frontiers in Pharmacology, 2021
Photothermal therapy (PTT) has become effective method for the treatment of malignant cancer. The development of PTT system with high anti-tumour effect is still the feasible research direction. Here, a new type of gold nanorods (AuNRs)-doxorubicin (DOX)/
Que Lin, Que Lin, Mao Jia, Mao Jia, Yi Fu, Bei Li, Zhigang Dong, Xiaoya Niu, Zhen You   +8 more
doaj   +1 more source

Solvent-induced micelle formation in a hydrophobic interaction model

, 2004
We investigate the aggregation of amphiphilic molecules by adapting the two-state Muller-Lee-Graziano model for water, in which a solvent-induced hydrophobic interaction is included implicitly.
A. Ben-Naim, B. Normand, C. Tanford, F. H. Stillinger, G. Gompper, J. N. Israelachvili, N. Muller, P. De Los Rios, P. L. Privalov, S. H. Yalkowsky, S. Moelbert, W. Kauzmann, Y. Kita   +12 more
core   +1 more source