Results 151 to 160 of about 119,003 (273)

UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression

Cellular and Molecular Life Sciences, 2016
A. J. Deen, U. T. Arasu, S. Pasonen-Seppänen, A. Hassinen, P. Takabe, Sara Wojciechowski, R. Kärnä, K. Rilla, S. Kellokumpu, R. Tammi, M. Tammi, S. Oikari   +11 more
semanticscholar   +1 more source

Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1095-1104, April 2026.
Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo, Donna A. Volpe, Anik Chaturbedi, Aanchal Shah, Ashok Krishna, Paula L Hyland, Giri Vegesna, Cheng‐Hui Hsiao, Ryan De Palma, Melanie Fein, Rodney Rouse, Jeffry Florian   +11 more
wiley   +1 more source

Phylogenetic analysis reveals diversity in glycan biosynthesis in "<i>Candidatus</i> Accumulibacter". [PDF]

Biofilm
Eerden SA, Abeel T, van Loosdrecht MCM, Roy S.   +3 more
europepmc   +1 more source

A comprehensive review of UDP-glucuronosyltransferase and esterases for drug development.

Drug Metabolism and Pharmacokinetics, 2015
Shingo Oda, T. Fukami, T. Yokoi, M. Nakajima   +3 more
semanticscholar   +1 more source

Different Transcriptional Responses to Developmental Versus Short‐Term Acclimation Temperatures in Pieris rapae

Ecology and Evolution, Volume 16, Issue 4, April 2026.
Transcriptomic data indicates that gene expression responses underlying developmental thermal plasticity differ from those of short‐term acclimation temperature in the butterfly Pieris rapae. We also identify a small subset of genes for which expression levels depend on the interaction of developmental temperature and short‐term acclimation temperature.
Samantha L. Sturiale, Lorrie Le Yi He, Katherine H. Malinski, Christopher S. Willett, Joel G. Kingsolver, Leslie Ries, Peter A. Armbruster   +6 more
wiley   +1 more source

Carnosine protects human microglia against Aβ oligomers through a multimodal mechanism of action: inhibition of oxidative stress, rescue of cellular energy status, and enhancement of phagocytosis. [PDF]

Front Immunol
Privitera A, Cardaci V, Zupan MC, Di Pietro L, Carota G, Sibbitts J, Mangione R, Graziani A, Buccarello L, Bellia F, Di Pietro V, Lazzarino G, Lunte SM, Hartley MD, Caraci F, Tavazzi B, Maiani E, Amorini AM, Lazzarino G, Caruso G.   +19 more
europepmc   +1 more source

Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study

NMR in Biomedicine, Volume 39, Issue 4, April 2026.
Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano, Carmen Marino, Manuela Grimaldi, Michela Buonocore, Angelo Santoro, Anna Maria D'Ursi   +5 more
wiley   +1 more source

P.F. Strawson (1919-2006)

Isegoría, 2006
M. E. Orellana Benado
doaj  

Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells. [PDF]

Nat Chem Biol
Li Z, Chawla H, Di Vagno L, Ní Cheallaigh A, Critcher M, Sammon D, Gonzalez-Rodriguez E, Briggs DC, Chung N, Chang V, Mahoney KE, Cioce A, Bineva-Todd G, Wang PY, Liu YC, Murphy LD, Chen YH, Narimatsu Y, Miller RL, Willems LI, Malaker SA, Huang ML, Miller GJ, Hohenester E, Schumann B.   +24 more
europepmc   +1 more source

Tetraopes Milkweed Beetle Genomes Elucidate the Adaptive Basis of a Temperate Coevolutionary Radiation

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT The coevolutionary radiation of 27 species of Tetraopes longhorned beetles and their Asclepias milkweed hosts represents a classic example of adaptive evolution driven by plant chemical defences and herbivore counteradaptations. Investigations to date, however, have focused on a single species, Tetraopes tetrophthalmus, which feeds on the ...
Sangil Kim, Brian D. Farrell
wiley   +1 more source