Assessing Extracellular Vesicle Proteins as Predictive Biomarkers for Developing Type 1 Diabetes
PROTEOMICS, EarlyView.ABSTRACT Plasma extracellular vesicles (EVs) are considered excellent sources for biomarker discovery since they carry signatures of their cellular origin and disease processes. In this paper, we evaluate the potential of plasma EV proteomics analysis for identifying predictive biomarkers of developing type 1 diabetes (T1D), which results from ...
Panshak P. Dakup +9 more
wiley +1 more source
A simple, rapid and cost-effective UHPLC-MS/MS method for simultaneous quantitation of seven antiepileptic drugs/metabolites in human serum. [PDF]
J Mass Spectrom Adv Clin LabFu X, Li X, He H.
europepmc +1 more source
Planting for healthy air: Urban biodiversity enhances natural chemical environments
PLANTS, PEOPLE, PLANET, EarlyView.Cities urgently need nature to improve public health, support biodiversity, and increase resilience to climate change. Yet not all green spaces offer the same benefits. In this study, we show that more diverse urban plantings create richer “chemical environments”; subtle, naturally scented atmospheres formed by plant emissions that can influence how ...
Aurora Ruggeri +5 more
wiley +1 more source
Targeted Determination of Residual Sex Hormones in Cosmetics Using Magnetic Solid-Phase Extraction with Isotope-Labeled Internal Standards by UHPLC-MS/MS. [PDF]
MoleculesDong Y +5 more
europepmc +1 more source
Pest Management Science, EarlyView.The cabbage stem flea beetle (Psylliodes chrysocephala) is a major pest of winter oilseed rape (Brassica napus). We tested B. napus and Sinapis alba seedlings for feeding resistance and underlying chemical defenses. S. alba was least damaged, while metabolite profiles revealed resistance‐linked compounds, highlighting breeding potential for insect ...
Daniel Rüde +4 more
wiley +1 more source
Optimization and validation of a targeted high-throughput UHPLC-MS/MS method for the analysis of multiple mycotoxins in chicken serum, egg yolk and white. [PDF]
Mycotoxin ResKabeta T +3 more
europepmc +1 more source
Pest Management Science, EarlyView.Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song +5 more
wiley +1 more source
Comparison of the pharmacokinetic profiles of three triterpenoids after oral administration of a cucurbitacin tablet and nanosuspension by UHPLC-MS/MS. [PDF]
Front PharmacolZhang CN +8 more
europepmc +1 more source
Pest Management Science, EarlyView.Alcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. Fractionation followed by metabolomic analysis revealed putative terpenoids as the main components of the active fractions. Specifically, 7‐methylrosmanol, 12‐O‐methylcarnosic acid, carnosic acid, and carnosol were identified as ...
Anna Smaldone +5 more
wiley +1 more source
Stability studies of cynaropicrin–major sesquiterpene lactone of Cynara cardunculus leaves
Pest Management Science, EarlyView.This study investigated its stability under high temperature and pH, mimicking agronomic extremes and under soil context. Bioassays demonstrated that degradation products exhibited higher phytotoxic activity than cynaropicrin and deacylcynaropicrin. This is the first study about cynaropicrin's stability, characterizing degradation products, and their ...
Daniela Rosa +6 more
wiley +1 more source