Results 111 to 120 of about 2,976,642 (307)

UHPLC/TOF-MS method development for untargeted metabolic analysis in urine

, 2010
UHPLC/TOF-MS method development for untargeted metabolic analysis in ...
Wormann K., 许国旺, WormannK., FeketeA., LehmannR., ForcisiS., Schmitt-KopplinP.   +6 more
core  

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Dual-mode screening system for rapid and accurate aflatoxin B1 detection in edible oils

Food Chemistry: X
This study established a dual-mode system integrating a portable flow cytometer with UHPLC-QqQ MS/MS for rapid AFB1 detection in edible oils. A competitive immunofluorescence sensor used streptavidin-magnetic microspheres with biotin-AFB1-BSA, AFB1 ...
Guangyao Ying, Tingting Wang, Kunlun Li, Zheng Lu, Yuxin Wang, Gangjian Lin, Jun Li, Huili Xia, Liang Hong   +8 more
doaj   +1 more source

Fast protein digestion and identification using hybrid silica monolith based metal-ion chelately immobilized trypsin microreactor and uHPLC-MS/MS

, 2008
Fast protein digestion and identification are indispensable in mosr proteomic study.Immobilized enzyme microreactors,especially those based on monoliths, recently have been paid much attention due to the fast digestion speed and the avoidance of enzyme ...
马俊锋, 梁振, 张玉奎, 张维冰, 张丽华   +4 more
core  

The serum paroxetine levels assessed by UHPLC-MS/MS.

, 2016
The serum paroxetine levels assessed by UHPLC-MS/MS.
Jørgen Bo Hasselstrøm (3332595), Ove Wiborg (493243), Mithula Sivasaravanaparan (127176), Louise Ørum Olesen (3332598), Bente Finsen (3332592), Elena V. Bouzinova (493242), Maurizio Severino (318869)   +6 more
core   +1 more source

Development of UHPLC-MS/MS and UHPSFC-MS/MS methods for determination of selected ochratoxins [PDF]

, 2022
Charles University, Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Kristián Kretek Supervisor: prof. PharmDr. Lucie Nováková, Ph.D.
Kretek, Kristián
core  

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt

Advanced Science, EarlyView.
A natural microbial consortium employing a cross‐feeding strategy forms a stratified biofilm that promotes endophytic colonization of auxotrophic Flavobacterium. This enhanced colonization activates plant systemic resistance, effectively suppressing Fusarium wilt.
Xianfeng Ye, Changsheng Xu, Shuai Yao, Jiming Shen, Zeyuan Li, Yu Zhang, Fan Wu, Xinjie Li, Yanling Ji, Lei Zhang, Yan Huang, Zhoukun Li, Huayu Qin, Zhongli Cui   +13 more
wiley   +1 more source

Systematic Profiling of the Multicomponents and Authentication of Erzhi Pill by UHPLC/Q-Orbitrap-MS Oriented Rapid Polarity-Switching Data-Dependent Acquisition and Selective Monitoring of the Chemical Markers Deduced from Fingerprint Analysis

Molecules, 2018
The analytical platform UHPLC/Q-Orbitrap-MS offers a solution to quality investigation of TCM with high definiteness. Using Erzhi Pill (EZP) as a case, we developed UHPLC/Q-Orbitrap-MS based approaches to achieve systematic multicomponent identification ...
Li Jia, Lingling Fu, Xiaoyan Wang, Wenzhi Yang, Hongda Wang, Tiantian Zuo, Chunxia Zhang, Ying Hu, Xiumei Gao, Lifeng Han   +9 more
doaj   +1 more source

Method development and validation for acrylamide in potato cutlet by UHPLC-MS/MS

Food Control, 2023
A. Kumari, B. Bhattacharya, T. Agarwal, V. Paul, Vaibhav Kumar Maurya, S. Chakkaravarthi, J. Simal-gandara   +6 more
semanticscholar   +1 more source