Results 141 to 150 of about 7,495,371 (267)

Correction: Enhancement of Apiaceae pre‑germination embryo growth, mericarp ageing resilience and germination differs between hormone, gas plasma, and hydropriming technologies. [PDF]

Planta
Fatelnig LMM, Walker M, Grainge G, Hourston JE, Kennedy S, Turečková V, Novák O, Tarkowská D, Strnad M, Nakabayashi K, Steinbrecher T, Leubner-Metzger G.   +11 more
europepmc   +1 more source

"You Can't Study if you're Hungry" Report of a Parliamentary Delegation to Tanzania\ud [PDF]

, 2014
RESULTS UK, RUK
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Translation approaches to support systemic anti-cancer therapy consent for individuals with limited English proficiency. [PDF]

Support Care Cancer
Hibbs SP, Nizam R, Tanzim U, Aiken L, Habib S, Hodgson S, Williams J, Januszewski A, Hantel A, Uddin MS, Isaacs T, Bajaj B, Cockburn O, Islam A, Pratt G, Federici FM.   +15 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Lessons to be learned: a retrospective study of MBRRACE-UK perinatal mortality surveillance (2015-2024) to identify maternity services most consistently reporting higher- and lower-than-average deaths. [PDF]

J Public Health (Oxf)
McDonagh Hull P, Boulton T, Lashewicz B.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Publisher Correction: Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome. [PDF]

Nat Commun
Balmus G, Larrieu D, Barros AC, Collins C, Abrudan M, Demir M, Geisler NJ, Lelliott CJ, White JK, Karp NA, Atkinson J, Kirton A, Jacobsen M, Clift D, Rodriguez R, Sanger Mouse Genetics Project, Adams DJ, Jackson SP.   +17 more
europepmc   +1 more source

Jurassic dinosaur tracks and trackways of the Cleveland Basin, Yorkshire: preservation, diversity and distribution [PDF]

, 2014
Romano, Michael, Whyte, Martin A.
core