Results 61 to 70 of about 7,495,371 (267)

Are European Works Councils ready for Brexit? : An inside look [PDF]

, 2020
On 31 January 2020, at 23:00, the United Kingdom (UK) officially ceased to be a member of the European Union (EU). One of the many areas that will likely be directly affected with regard to workers’ rights is the organisation and functioning of European ...
De Spiegelaere, Stan, Jagodzinski, Romuald   +1 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluating the effectiveness of the Drink Less smartphone app for reducing alcohol consumption compared with usual digital care: a comprehensive synopsis from a 6-month follow-up RCT

Public Health Research
Background Digital interventions can be effective for reducing alcohol consumption. However, most digital interventions that have been evaluated are websites and there is little evidence on the effectiveness of smartphone apps, especially in a United ...
Claire Garnett, Melissa Oldham, Gemma Loebenberg, Larisa Dinu, Emma Beard, Colin Angus, Robyn Burton, Matt Field, Felix Greaves, Matthew Hickman, Eileen Kaner, Susan Michie, Marcus Munafò, Elena Pizzo, Jamie Brown   +14 more
doaj   +1 more source

The Novel Psychoactive Substances in the UK Project: empirical and conceptual review work to produce research recommendations

Public Health Research, 2017
Background: Although illegal drug use has largely been declining in the UK over the past decade, this period has witnessed the emergence of a range of novel psychoactive substances (NPS) (‘legal highs’).
Noreen D Mdege, Nick Meader, Charlie Lloyd, Steve Parrott, Jim McCambridge   +4 more
doaj   +1 more source

Nationalising English Legal Language Pedagogy in L2 Genre-Based Writing: Legal Problem Question in the UK Loci of Law. Implications and Challenges for the Pluricentricity of a Legal English Pedagogy

Iperstoria, 2011
It is widely recognised that the prominent role of English as a global language affects the nature and form of English used in cross-cultural settings.
Girolamo Tessuto
doaj   +1 more source

Le mouvement à l’école, quels bénéfices ? [PDF]

, 2015
Ce travail traite de l’apport du mouvement à l’école en dehors des heures d’éducation physique. Après quelques informations sur les besoins de l’enfant, le Trouble du Déficit d’Attention avec ou sans Hyperactivité (TDAH), la Brain Gym, plus ...
Bernasconi, Kevin, L'Eplatenier, Yves
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Chinese Direct Investments in the EU and the Changing Political and Legal Frameworks [PDF]

Contemporary Chinese Political Economy and Strategic Relations: An International Journal, 2020
This paper seeks to shed light on the key geopolitical interests of European countries (EU members) as for technology transfer from China and to China. The paper focuses on the policies of the key EU members (Germany, France, Italy and the United Kingdom)
István Csaba Moldicz
doaj  

Why did the Swiss electorate refuse the initiative on Unconditional Basic Income ("UBI") and what this vote would suppose for Switzerland in the future ? [PDF]

, 2017
Working conditions and the work environment have evolved significantly over the last decades. As one of the consequences of automation and productivity gains, working time has decreased, and unemployment has increased since the middle of the XIX century.
Esposito-Cano, Antoinette, Oliveira, Ricardo de   +1 more
core