Results 71 to 80 of about 9,979,066 (266)
Cancer Research UK Cancer Awareness Measures, February 2022
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller, J., Ramirez, A.,
Cancer Research UK
core +2 more sources
Brexit and the Anglosphere: an intra-industry trade opportunity for India? [PDF]
Eastern Journal of European Studies, 2020 The present paper outlines a functionalist approach to the complex “Brexit” phenomenon, exploring those opportunities that can be derived of it for third countries, unaware of the upheaval European scenario, as could be the case of India.
Francisco José CALDERÓN VÁZQUEZ +2 more
doaj
Value in Health, 1998 Making decisions on lipid-lowering treatment varies across Europe. Legislation differs from country to country, so it is difficult to generalize about European policy. From the perspective of the United Kingdom, this paper addresses the impact of rationing, cost containment, information feedback, fund-holding and drug expenses. Primary versus secondary
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Cancer Research UK Cancer Awareness Measures, September 2023
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller, J., Ramirez, A.,
Cancer Research UK
core +2 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Media and CommunicationWhere does innovation in journalism come from, how is it implemented, and what factors drive or hinder its development? Scholars have explored these questions from different perspectives for over two decades.
Klaus Meier +9 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Social Work/Maatskaplike Werk, 2006 This article reports research that was undertaken to uncover generalisations pertaining to the migration of South African social workers to the United Kingdom (UK).
Lambert K Engelbrecht
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source