Results 151 to 160 of about 558,447 (316)

Effect of Counterbody Material on the Boundary Lubrication Behavior of Commercially Pure Titanium in a Motor Oil

open access: yesLubricants
Titanium possesses many useful properties and is a technologically important material in engineering. However, lubrication of titanium has long been a problem that has prevented titanium from being more widely used.
Yizhao Liu   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Building a better PR-journalist relationship: a social media segmentation of UK journalists

open access: yes, 2014
This research aims to help public relations (PR) improve their relationship with journalists by exploring differences in the use, views, attitudes and behaviours towards social media and the contact methods with PR-practitioners.
Pole, K.
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Social PR study 2015: a study of social media use among PR professionals [PDF]

open access: yes, 2015
This study aims to explore and understand how social media impacts PR professionals and their media relationships. It compares the results with research from the published Social Journalism Study 2015 and notes that PR professionals and journalists are ...
Cision UK, Pole, K.
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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