Results 61 to 70 of about 664,080 (329)

Early Antiretroviral Therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy: Evidence from the

hildren with
    H
IV
    E
arly Anti
    r
etroviral Therapy (CHER) Study

open access: yesBMC Research Notes, 2011
Background Although otorrhea occurs commonly in HIV-infected infants, there are few data. We compared the incidence of otorrhea in infants receiving early vs deferred ART in the Children with HIV Early Antiretroviral (CHER) trial.
Cornell Morna   +10 more
doaj   +1 more source

Sensor-Based Categorization of Upper Limb Performance in Daily Life of Persons With and Without Neurological Upper Limb Deficits

open access: yesFrontiers in Rehabilitation Sciences, 2021
Background: The use of wearable sensor technology (e. g., accelerometers) for tracking human physical activity have allowed for measurement of actual activity performance of the upper limb (UL) in daily life.
Jessica Barth   +8 more
doaj   +1 more source

Silicified Wood‐Inspired, High‐Strength Fire‐Resistant Chitin‐Based Aerogels for Sustainable High‐Temperature Thermal Insulation

open access: yesAdvanced Functional Materials, EarlyView.
Inspired by natural silicified wood, a biomimetic mineralized chitin‐derived aerogel is constructed. It can withstand 81 000 times its own weight, and its backside temperature is 130.4°C after exposure to ∼1300°C butane flame for 600 s, exhibiting high‐strength, fire‐resistance, and super thermal‐insulation properties.
Kai Xu   +11 more
wiley   +1 more source

Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin

open access: yesBMC Cell Biology, 2011
Background The amyloid precursor protein (APP) is cleaved by β- and γ-secretases to generate toxic amyloid β (Aβ) peptides. Alternatively, α-secretases cleave APP within the Aβ domain, precluding Aβ formation and releasing the soluble ectodomain, sAPPα ...
Slack Barbara E   +2 more
doaj   +1 more source

Urinary phytoestrogens and the risk of uterine leiomyomata in US women

open access: yesBMC Women's Health, 2023
Background Uterine leiomyomata (UL) is a common gynecological disease in women. Studied on the relationship between single metabolites of urinary phytoestrogens and UL, especially for the combined effects of mixed metabolites on UL still are insufficient.
Fang Yang, Youguo Chen
doaj   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

open access: yesAdvanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett   +19 more
wiley   +1 more source

EXercising with

omputers in
    L
ater
    L
ife (EXCELL) - pilot and feasibility study of the acceptability of the Nintendo® WiiFit in community-dwelling fallers

open access: yesBMC Research Notes, 2010
Background Falls management programmes have been instituted to attempt to reduce falls. This pilot study was undertaken to determine whether the Nintendo® WiiFit was a feasible and acceptable intervention in community-dwelling older fallers.
Williams Marie A   +3 more
doaj   +1 more source

Management of an academic HPC cluster: The UL experience

open access: yesInternational Symposium on High Performance Computing Systems and Applications, 2014
The intensive growth of processing power, data storage and transmission capabilities has revolutionized many aspects of science. These resources are essential to achieve high-quality results in many application areas.
Sébastien Varrette   +3 more
semanticscholar   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera   +6 more
wiley   +1 more source

Human homolog of Drosophila

airy and
    e
nhancer of
    s
plit 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancer

open access: yesMolecular Cancer, 2010
Background Neuronal synaptic junction protein δ-catenin (CTNND2) is often overexpressed in prostatic adenocarcinomas but the mechanisms of its activation are unknown.
Chen Yan-hua   +8 more
doaj   +1 more source

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