Results 31 to 40 of about 288,502 (268)

A randomized controlled trial of Shengji ointment combined with bromelain in promoting healing of tendon-exposed diabetic foot wounds: integrated 16S rDNA sequencing and metabolomics analysis

Frontiers in Pharmacology
BackgroundDiabetic foot tendon exposures are prone to infection, necrosis, and prolonged treatment cycle, not only hinder wound healing, but may also lead to amputation and even life-threatening. Utilizing Shengji ointment (a Traditional Chinese Medicine,
Xu Sun, Xu Sun, Xu Sun, Jielin Song, Jielin Song, Jielin Song, Junchao Sun, Junchao Sun, Junchao Sun, Zhaohui Zhang, Zhaohui Zhang, Zhaohui Zhang   +11 more
doaj   +1 more source

EXPERIMENTAL AND CLINICAL JUSTIFICATION WOUND-HEALING EFFECT OF BIOPLASTIC COLLAGEN MATERIAL IN THE TREATMENT OF CHRONIC WOUNDS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2021
Background. Due to the high prevalence of chronic wounds in patients with diabetes mellitus, the use of effective treatment for them is currently very important. Aim.
Dibirov M. D. , Gadzhimuradov R. U., Gabitov R. B. , Hlutkin A. V.   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

A rare cause of obscure gastrointestinal bleeding: Chronic enteropathy associated with SLCO2A1 mutation in a case from India

International Journal of Gastrointestinal Intervention
A 13-year-old boy presented with an 8-year history of repeated episodes of anemia. Laboratory investigations confirmed iron deficiency anemia due to occult blood loss from the gastrointestinal tract.
Shivani Chopra, Vikramaditya Rawat, Meghraj Ingle, Saiprasad Lad, Mit Shah, Deepak Sasikumar, Vinay Borkar, Yatin Lunagariya, Somraj Patil   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Co-creation of a gender responsive TB intervention in Nigeria: a researcher-led collaborative study

BMC Health Services Research
Background In Nigeria, men constitute over half of the people notified with tuberculosis (TB), experience longer delays before reaching care, and are estimated to account for two thirds of people who miss out on care. The higher TB risk and burden in men
Chukwuebuka Ugwu, Oluwatoyosi Adekeye, Beate Ringwald, Rachael Thomson, Obioma Chijioke-Akaniro, Chukwuma Anyaike, S Bertel Squire, John Bimba, Tom Wingfield   +8 more
doaj   +1 more source

Detection of Ulcerative Colitis Lesions from Weakly Annotated Colonoscopy Videos Using Bounding Boxes

Gastrointestinal Disorders
Ulcerative colitis is a chronic disease characterized by bleeding and ulcers in the colon. Disease severity assessment via colonoscopy videos is time-consuming and only focuses on the most severe lesions.
Safaa Al-Ali, John Chaussard, Sébastien Li-Thiao-Té, Éric Ogier-Denis, Alice Percy-du-Sert, Xavier Treton, Hatem Zaag   +6 more
doaj   +1 more source

A clinical study of risk factors associated with amputation in diabetic foot disease patients attending a tertiary care hospital in a rural setting

Journal of Current Research in Scientific Medicine, 2020
Background: Diabetes mellitus is a disease of complications, which is rapidly increasing in prevalence worldwide. The total population affected by diabetes is projected to rise from 171 million in 2000 to 366 million by 2030.
Taraka Krishna Nulukurthi, Sistla Raj Kumar, Lakshmi Venkata Simhachalam Kutikuppala   +2 more
doaj   +1 more source

Evidence for Natural Products as Alternative Wound-Healing Therapies

Biomolecules, 2023
Chronic, non-healing wounds represent a significant area of unmet medical need and are a growing problem for healthcare systems around the world. They affect the quality of life for patients and are an economic burden, being difficult and time consuming ...
Rachael L. Moses, Thomas A. K. Prescott, Eduard Mas-Claret, Robert Steadman, Ryan Moseley, Alastair J. Sloan   +5 more
doaj   +1 more source