Results 41 to 50 of about 287,233 (268)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

A rare cause of obscure gastrointestinal bleeding: Chronic enteropathy associated with SLCO2A1 mutation in a case from India

International Journal of Gastrointestinal Intervention
A 13-year-old boy presented with an 8-year history of repeated episodes of anemia. Laboratory investigations confirmed iron deficiency anemia due to occult blood loss from the gastrointestinal tract.
Shivani Chopra, Vikramaditya Rawat, Meghraj Ingle, Saiprasad Lad, Mit Shah, Deepak Sasikumar, Vinay Borkar, Yatin Lunagariya, Somraj Patil   +8 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Co-creation of a gender responsive TB intervention in Nigeria: a researcher-led collaborative study

BMC Health Services Research
Background In Nigeria, men constitute over half of the people notified with tuberculosis (TB), experience longer delays before reaching care, and are estimated to account for two thirds of people who miss out on care. The higher TB risk and burden in men
Chukwuebuka Ugwu, Oluwatoyosi Adekeye, Beate Ringwald, Rachael Thomson, Obioma Chijioke-Akaniro, Chukwuma Anyaike, S Bertel Squire, John Bimba, Tom Wingfield   +8 more
doaj   +1 more source

Detection of Ulcerative Colitis Lesions from Weakly Annotated Colonoscopy Videos Using Bounding Boxes

Gastrointestinal Disorders
Ulcerative colitis is a chronic disease characterized by bleeding and ulcers in the colon. Disease severity assessment via colonoscopy videos is time-consuming and only focuses on the most severe lesions.
Safaa Al-Ali, John Chaussard, Sébastien Li-Thiao-Té, Éric Ogier-Denis, Alice Percy-du-Sert, Xavier Treton, Hatem Zaag   +6 more
doaj   +1 more source

A clinical study of risk factors associated with amputation in diabetic foot disease patients attending a tertiary care hospital in a rural setting

Journal of Current Research in Scientific Medicine, 2020
Background: Diabetes mellitus is a disease of complications, which is rapidly increasing in prevalence worldwide. The total population affected by diabetes is projected to rise from 171 million in 2000 to 366 million by 2030.
Taraka Krishna Nulukurthi, Sistla Raj Kumar, Lakshmi Venkata Simhachalam Kutikuppala   +2 more
doaj   +1 more source

Evidence for Natural Products as Alternative Wound-Healing Therapies

Biomolecules, 2023
Chronic, non-healing wounds represent a significant area of unmet medical need and are a growing problem for healthcare systems around the world. They affect the quality of life for patients and are an economic burden, being difficult and time consuming ...
Rachael L. Moses, Thomas A. K. Prescott, Eduard Mas-Claret, Robert Steadman, Ryan Moseley, Alastair J. Sloan   +5 more
doaj   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source

Hand, foot and mouth disease

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Hand, foot and mouth disease (HFMD) is an acute viral illness with a distinct clinical presentation of oral and characteristic distal extremity lesions. Knowledge of this is important for the dentists as the oral lesions are the first clinical signs and ...
Radhika Muppa, Prameela Bhupatiraju, Mahesh Duddu, Arthi Dandempally   +3 more
doaj   +1 more source