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The burden of inflammatory bowel disease (IBD) in Australia is increasing but national data about the current prevalence are limited. We aimed to estimate the prevalence of IBD (including Crohn's disease, ulcerative colitis and unspecified IBD) as well ...
Doreen Busingye+2 more
doaj +3 more sources
Five mucosal transcripts of interest in ulcerative colitis identified by quantitative real-time PCR: a prospective study [PDF]
Background The cause and pathophysiology of ulcerative colitis are both mainly unknown. We have previously used whole-genome microarray technique on biopsies obtained from patients with ulcerative colitis to identifiy 5 changed mucosal transcripts.
Kvifors Eva+4 more
doaj +4 more sources
Smoking and nicotine in inflammatory bowel disease: good or bad for cytokines? [PDF]
Smoking has either a beneficial or harmful effect on the course and recurrence of ulcerative colitis and Crohn's disease respectively. Transdermal application of nicotine had similar effects in ulcerative colitis and therefore was considered to be an ...
F. J. Zijlstra
doaj +5 more sources
Identification of symptom domains in ulcerative colitis that occur frequently during flares and are responsive to changes in disease activity [PDF]
Background Ulcerative colitis disease activity is determined by measuring symptoms and signs. Our aim was to determine which symptom domains are frequent and responsive to change in the evaluation of disease activity, which are those defined by three ...
Wang Sijian+8 more
doaj +5 more sources
Anatomical Region of the Colon as an Influencing Factor for Ulcerative Colitis Development [PDF]
Objectives: To determine if the anatomical location and extent of ulcerative inflammation influences the primary development of ulcerative colitis by defining the primary starting locations of ulcerative inflammation processes and determining the ...
Enkhbaatar Tseden+2 more
doaj +3 more sources
Ulcerative colitis is an idiopathic, chronic inflammatory disorder of the colonic mucosa, which starts in the rectum and generally extends proximally in a continuous manner through part of, or the entire, colon; however, some patients with proctitis or left-sided colitis might have a caecal patch of inflammation.
Daniel, El Fassi, Claus H, Nielsen
+9 more sources
Role of Toll-Like Receptor 5 in the Development of Ulcerative Colitis [PDF]
Inflammatory bowel disease (ulcerative colitis and Crohn’s disease) is a remitting and relapsing disease that affects millions of people worldwide. In the intestine, homeostasis between repair and signaling of the proinflammatory of the immune system is ...
A Falah Alshimerry+2 more
doaj +1 more source
Identification of an Anti–Integrin αvβ6 Autoantibody in Patients With Ulcerative Colitis [PDF]
指定難病「潰瘍性大腸炎」の自己抗体発見 --新たな診断や治療開発へ--. 京都大学プレスリリース. 2021-03-09.Background and Aims: Ulcerative colitis is the most frequent type of inflammatory bowel disease and is characterized by colonic epithelial cell damage.
Chiba, Tsutomu+27 more
core +1 more source
The LUCID study: living with ulcerative colitis; identifying the socioeconomic burden in Europe
Background Ulcerative colitis (UC) is an inflammatory bowel disease with increasing prevalence worldwide. Current treatment strategies place considerable economic and humanistic burdens on patients.
Leonardo Ruiz-Casas+14 more
doaj +1 more source
Ulcerative colitis is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. The pathogenesis is multifactorial, involving genetic predisposition, epithelial barrier defects, dysregulated immune responses, and environmental factors.
Ungaro, Ryan+4 more
openaire +3 more sources