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The Lancet, 2017 Ulcerative colitis is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. The pathogenesis is multifactorial, involving genetic predisposition, epithelial barrier defects, dysregulated immune responses, and environmental factors.
Ungaro, Ryan +4 more
openaire +4 more sources
Mayo Clinic Proceedings, 2019 Ulcerative colitis (UC) is a chronic inflammatory bowel disease that can involve any aspect of the colon starting with mucosal inflammation in the rectum and extending proximally in a continuous fashion. Typical symptoms on presentation are bloody diarrhea, abdominal pain, fecal urgency, and tenesmus.
Joseph D. Feuerstein +2 more
openaire +3 more sources
The Lancet, 2012 Ulcerative colitis is an idiopathic, chronic inflammatory disorder of the colonic mucosa, which starts in the rectum and generally extends proximally in a continuous manner through part of, or the entire, colon; however, some patients with proctitis or left-sided colitis might have a caecal patch of inflammation.
Ordás, Ingrid +4 more
+7 more sources
Role of Toll-Like Receptor 5 in the Development of Ulcerative Colitis [PDF]
Archives of Razi Institute, 2021 Inflammatory bowel disease (ulcerative colitis and Crohn’s disease) is a remitting and relapsing disease that affects millions of people worldwide. In the intestine, homeostasis between repair and signaling of the proinflammatory of the immune system is ...
A Falah Alshimerry +2 more
doaj +1 more source
Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis.
New England Journal of Medicine, 2021 BACKGROUND Ozanimod, a selective sphingosine-1-phosphate receptor modulator, is under investigation for the treatment of inflammatory bowel disease. METHODS We conducted a phase 3, multicenter, randomized, double-blind, placebo-controlled trial of ...
W. Sandborn +15 more
semanticscholar +1 more source
Ulcerative colitis: an update.
Clinical medicine (London), 2021 Ulcerative colitis is a relapsing and remitting disease that is increasing in incidence and prevalence. Management aims to achieve rapid resolution of symptoms, mucosal healing and improvement in a patient's quality of life.
J. Segal, J. LeBlanc, A. Hart
semanticscholar +1 more source
The LUCID study: living with ulcerative colitis; identifying the socioeconomic burden in Europe
BMC Gastroenterology, 2021 Background Ulcerative colitis (UC) is an inflammatory bowel disease with increasing prevalence worldwide. Current treatment strategies place considerable economic and humanistic burdens on patients.
Leonardo Ruiz-Casas +14 more
doaj +1 more source
Modern principles of conservative treatment of mild and moderate forms of ulcerative colitis
Лечащий Врач, 2022 Ulcerative colitis is a chronic disease characterized by inflammation that usually begins in the rectum and diffusely spreads proximally, involving part or all of the colonic mucosa.
O. V. Golovenko
doaj +1 more source
Scientific Reports, 2021 Ulcerative colitis is a chronic, idiopathic, and inflammatory disease of the rectal and colonic mucosa, the behavior of which is of heterogeneity in individuals.
Lijie Lai +4 more
doaj +1 more source
Medicina, 2023 Background and Objectives: Atherosclerosis is one of inflammatory bowel disease’s most significant cardiovascular manifestations. This research aimed to examine the relationship between biochemical, haemostatic, and immune parameters of atherosclerosis ...
Sofija I. Lugonja +9 more
doaj +1 more source