Results 161 to 170 of about 269,130 (350)

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

open access: yesFood Frontiers, EarlyView.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh   +11 more
wiley   +1 more source

Exploring the health benefits of gut microbiota metabolites on combating ulcerative colitis via network pharmacology, bioinformatics and molecular docking

open access: yesScientific Reports
Ulcerative colitis (UC) is a leading health challenge worldwide. The evidence of the benefits of gut microbiota metabolites for the treatment of ulcerative colitis is accumulating, but the underlying mechanism remains to be further elucidated. Hence, the
Weiguo Yao   +3 more
doaj   +1 more source

A Mucoadhesive Hydrogel for Precise Resveratrol Delivery in the Management of Inflammatory Bowel Disease

open access: yesFood Frontiers, EarlyView.
CMTR‐Gel targeting to the inflamed mucosa by electrostatic interactions. ABSTRACT Natural drug‐food homology compounds have vast therapeutic potential, particularly for inflammatory bowel disease (IBD), but their poor water solubility, instability, and limited mucosal availability hinder their clinical translation.
Wenqiu Xu   +7 more
wiley   +1 more source

Signifiance of autoimmune reactions to pancreatic juice in Crohn´s disease [PDF]

open access: yes, 1988
Goebell, Harald   +5 more
core   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

open access: yesiMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

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