Results 221 to 230 of about 149,982 (306)

Protective Properties of the White Button Mushroom, Agaricus bisporus, in a Mouse Model of Colitis

Molecular Nutrition &Food Research, EarlyView.
In this study, whole mushroom powder (WMP) from white button mushrooms was tested for gut health benefits. In vitro digested WMP (IVD‐WMP) could reduce the permeability of a gastrointestinal cell layer. In mouse studies, WMP was tested as a preventative and a treatment for dextran sulfate sodium (DSS) induced colitis. WMP could improve recovery, reduce
Elaine Dempsey, Aaron M. Walsh, Supriya Yadav, Jude Wilson, Frederick J. Sheedy, Sinead C. Corr   +5 more
wiley   +1 more source

Role of endoscopic ultrasound as a predictor of histological healing in ulcerative colitis. [PDF]

Ann Med
Tian J, Wang W, Liu Y, Zhang X, Zhao H, Qu H.   +5 more
europepmc   +1 more source

Protective Effects of Human Milk Oligosaccharides (hMOs) on Analgesic, Nonsteroidal Anti‐inflammatory Drugs (NSAIDs)‐Induced Disruption of Gut Barrier Integrity in Cocultures Mimicking Neuro‐Gut Epithelial Cell Crosstalk

Molecular Nutrition &Food Research, EarlyView.
Nerve cells partially mitigate indomethacin‐induced tight junction dysregulation in neuro‐gut epithelial cell cocultures. Human milk oligosaccharides 2′‐ and 3‐fucosyllactose (2′‐FL and 3‐FL) protect the neuro‐gut epithelial barrier from indomethacin‐induced damage. This protection is stronger in cocultures with higher nerve cell densities.
Xiaochen Chen, Naschla Gasaly, Marthe T. C. Walvoort, Paul de Vos   +3 more
wiley   +1 more source

Comparative Risk of Developing Interstitial Cystitis With Childhood Gastrointestinal, Urological, Autoimmune, or Psychiatric Disorders

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Interstitial cystitis (IC) is a chronic urological condition associated with significant discomfort, posing diagnostic and therapeutic challenges. Although its etiology remains unclear, early‐life conditions such as gastrointestinal (GI) disorders, urological anomalies (UA), psychiatric disorders (PD), and autoimmune diseases (AD) have ...
Mohammad Alipour‐Vaezi, Robert S. McNamara, Margaret R. Rukstalis, Emily C. Gentry, Daniel B. Rukstalis, Donald B. Penzien, Kwok‐Leung Tsui, Huaiyang Zhong   +7 more
wiley   +1 more source

Sulfide Quinone Oxidoreductase Alleviates Acute Ulcerative Colitis by Regulating Mitochondrial Dysfunction. [PDF]

MedComm (2020)
Ma H, Fu S, Huang C, Han N, Cai F, Li D, Cheng J, Zhuang H, Hua ZC.   +8 more
europepmc   +1 more source

Lipid‐associated macrophages are more abundant in subcutaneous than visceral adipose tissue in patients with obesity

Obesity, EarlyView.
Abstract Objective Because white adipose tissue is infiltrated by several immune cells and their signature in individuals with obesity has not been fully characterized, we wanted to study the most abundant population, which is macrophages, a subtype of myeloid cell. Methods To address this objective, we performed transcriptomic analysis of subcutaneous
Marjorie Reyes‐Farias, Pablo Fernández‐García, Patricia Corrales, Lorena González, David Navarro‐Sanagustín, Andrea Soria‐Gondek, Silvia Pellitero, Jordi Tarascó, Pau Moreno, José M. Balibrea, Laia Gatell, Lauro Sumoy, María Galán, Ester Martínez, Francesc Villarroya, Rubén Cereijo, Laura Herrero, David Sánchez‐Infantes   +17 more
wiley   +1 more source

Etrasimod: Modulating Sphingosine-1-Phosphate Receptors to Treat Ulcerative Colitis. [PDF]

J Clin Med
Martinez-Molina C, González-Suárez B.
europepmc   +1 more source

Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer

The Journal of Pathology, EarlyView.
Abstract The CpG island methylator phenotype (CIMP) occurs in many colorectal cancers (CRCs). CIMP is closely associated with global hypermethylation and tends to occur in proximal tumours with microsatellite instability (MSI), but its origins have been obscure.
Joseph C Ward, Melissa Morgan, James Wood, Connor Woolley, Albert Antao Nobre de Menezes, Alina Finch, Kitty Sherwood, Qiwen Huang, Chloe S Henry, Juan Fernández‐Tajes, Ignacio Soriano, Steve Thorn, Isabelle Legge, James McCullagh, David Kerr, Rachel Kerr, Rahul K Hejmadi, Mark J Arends, The S:CORT Consortium, Richard Adams, Simon Bach, Andrew Beggs, Louise Brown, Francesca Buffa, Jean‐Baptiste Cazier, Enric Domingo, Andrew Blake, Che‐Hsi Wu, Ekaterina Chatzpili, Susan Richman, Philip Dunne, Paul Harkin, Geoff Higgins, Jim Hill, Chris Holmes, Denis Horgan, Rick Kaplan, Richard Kennedy, Mark Lawler, Simon Leedham, Ultan McDermott, Gillies McKenna, Gary Middleton, Dion Morton, Graeme Murray, Philip Quirke, Manuel Salto‐Tellez, Les Samuel, Anna Schuh, David Sebag‐Montefiore, Matt Seymour, Ricky Sharma, Richard Sullivan, Ian Tomlinson, Nicholas West, Richard Wilson, Enric Domingo, Timothy Maughan, Chiara Bardella, Ian Tomlinson   +59 more
wiley   +1 more source