Results 241 to 250 of about 215,870 (306)

Investigating the Effect of Tumour Necrosis Factor Antagonist on Olfaction

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives Tumour Necrosis factor antagonists is a potent anti‐inflammatory medication and has shown to improve olfactory function in murine models. The primary aim was to determine the effect of TNF antagonists on olfactory performance in humans.
Andreas Espehana, George Macfarlane, Elizabeth Mairenn Garden, Liam Lee, Gabija Klyvyte, Lavandan Jegatheeswaran, Rebecca Davies, Carl Philpott   +7 more
wiley   +1 more source

Histologic Assessment in Ulcerative Colitis: A Survey of Pathologists' Practices and Perspectives. [PDF]

Gastroenterology Res
Shenoy KD, Li J, Booth AL, Liu X.
europepmc   +1 more source

AMSC‐sEVs Ameliorated Crohn's Disease by Inhibiting Macrophage‐Myofibroblast Transition Through the Delivery of MFGE8

Cell Proliferation, EarlyView.
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie, Qiang Liu, Zhizhong Xiong, Jian Li, Ruiri Jin, Lei Lian, Zhengrong Li   +6 more
wiley   +1 more source

A Case of Blastomycosis Like Pyoderma Responsive to Intralesional Triamcinolone Acetonide Injections

Australasian Journal of Dermatology, EarlyView.
Dasmesh Sron, Andrew Swarbrick, Benjamin Wood, Justin Bui   +3 more
wiley   +1 more source

Downregulation of MLL1 Promotes Intestinal Epithelial Barrier Repair Through Gata4/Bmp4 Activation to Ameliorate Crohn's Disease‐Like Colitis in Mice

Cell Proliferation, EarlyView.
This study elucidates the pivotal regulatory role and mechanism of MLL1 in inflammatory bowel disease. Experimental data demonstrated elevated MLL1 expression levels in TNBS‐induced murine colitis models, with pharmacological inhibition of MLL1 significantly promoting recovery from CD‐like colitis by accelerating intestinal barrier restoration ...
Xue Song, Jing Li, Yue Chen, Bohan Li, Yi Yang, Xiaofan Guan, Xiaofeng Zhang, Lu Tao, Zhijun Geng, Lugen Zuo, Yueyue Wang, Lian Wang, Jianguo Hu   +12 more
wiley   +1 more source

Clinical Characteristics of Late-Onset (≥ 65 Years) Ulcerative Colitis: A Single-Center Retrospective Study. [PDF]

Gastroenterol Res Pract
Ito A, Koroku M, Murasugi S, Yonezawa M, Oomori T, Nakamura S, Tokushige K, Nakai Y.   +7 more
europepmc   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, EarlyView.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

Nimbolide ameliorates ARDS and ulcerative colitis by disrupting NLRP3 inflammasome activation. [PDF]

Commun Biol
Xu H, Lin Y, Luo W, Sheng S, Xu Y, Zhang Z.   +5 more
europepmc   +1 more source

Safety and Efficacy of Ozanimod in Patients With Moderately to Severely Active Ulcerative Colitis Stratified by Age. [PDF]

Inflamm Bowel Dis
Faye AS, Rubin DT, Siegel CA, Long MD, Khan N, Danese S, Irving PM, Cross RK, Blumenstein I, Armuzzi A, Horst SN, Dignass A, Kobayashi T, Lawlor G, Krakovich A, Petersen A, Liu Z, Wang D, Jain A, Ananthakrishnan AN, Sabino J.   +20 more
europepmc   +1 more source

Efficacy and Safety of Upadacitinib in a Case of Pediatric Acute Severe Ulcerative Colitis and Immune Thrombocytopenia. [PDF]

Inflamm Bowel Dis
Bocchini B, Martinelli M, Strisciuglio C, Stellato P, Fioretti MT, Staiano A, Miele E.   +6 more
europepmc   +1 more source