Results 341 to 350 of about 499,883 (421)

Patients' and gastroenterologists' preferences regarding outcomes and medication attributes in ulcerative colitis. [PDF]

open access: yesAnn Gastroenterol
Katsoula A   +7 more
europepmc   +1 more source

How “Sure” Are We About Precision Medicine in IBD?

open access: yes
United European Gastroenterology Journal, EarlyView.
Florian Tran, Konrad Aden
wiley   +1 more source

Systematic Multi‐Trait Study of Genetic Correlation and Causality Relationships Between General Medical Conditions and Mental Disorders

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Increasing evidence has highlighted bidirectional associations between mental disorders and general medical conditions, with underlying causes ranging from lifestyle habits and side effects from medications to genetic contributions. Novel methods now provide a way to estimate the shared genetic underpinnings and the possibility of
Ron Nudel   +2 more
wiley   +1 more source

CGRPβ suppresses the pathogenesis of ulcerative colitis via the immunoproteasome. [PDF]

open access: yesSci Rep
Shibao T   +7 more
europepmc   +1 more source

Using Biologics to Reduce Long‐Term Corticosteroid Use in Pyoderma Gangrenosum: Real‐World Evidence From Two Centres

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a challenging inflammatory skin disorder. While corticosteroids offer a rapid response, their long‐term risks necessitate alternative treatments. Objective To compare the long‐term effectiveness of biologic therapies versus systemic corticosteroids in PG management. Methods A retrospective analysis of 15
R. Cascio Ingurgio   +8 more
wiley   +1 more source

The Role of IgE in Crohn's Disease by Impairing the Capacity of Plasmacytoid Dendritic Cells to Generate FOXP3+ Tregs

open access: yesAllergy, EarlyView.
We uncover an unprecedented role for IgE in CD. CD patients, regardless of allergic status and similar to allergic patients, display higher levels of circulating IgE+ and FcεRI+ immune cells, including pDCs, which are concomitant to fewer Tregs. In vitro experiments show that the anti‐IgE monoclonal antibody omalizumab restores the ability of pDCs from
Andrés de la Rocha‐Muñoz   +11 more
wiley   +1 more source

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