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Ulipristal Acetate: Contraceptive or Contragestive?
Annals of Pharmacotherapy, 2011Ulipristal acetate is the first selective progesterone receptor modulator approved for postcoital contraception in the US. It appears to be significantly more effective in inhibition of ovulation than other forms of emergency contraception. However, ulipristal acetate is structurally similar to mifepristone, and several lines of evidence suggest that a
Jeffrey A Keenan
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Ulipristal acetate for emergency contraception
Drugs of Today, 2010Ulipristal acetate is a progesterone receptor modulator. As an emergency contraceptive, a 30-mg micronized formulation is effective for use up to 120 h from unprotected sexual intercourse. Ulipristal acetate acts as an antagonist of the progesterone receptor at the transcriptional level and a competitive antagonist of glucocorticoid receptor function ...
J A, Russo, M D, Creinin
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Drugs, 2012
Ulipristal acetate, a selective progesterone-receptor modulator, inhibits the proliferation and induces apoptosis of leiomyoma cells in vitro. It also modulates the expression of vascular endothelial growth factors and hormone receptors and modulates extracellular matrix breakdown in leiomyoma cells but not in myometrial cells.
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Ulipristal acetate, a selective progesterone-receptor modulator, inhibits the proliferation and induces apoptosis of leiomyoma cells in vitro. It also modulates the expression of vascular endothelial growth factors and hormone receptors and modulates extracellular matrix breakdown in leiomyoma cells but not in myometrial cells.
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Ulipristal Acetate for Emergency Contraception
Annals of Pharmacotherapy, 2011OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of data of ulipristal acetate, a new emergency contraceptive approved for use up to 120 hours after unprotected intercourse. DATA SOURCES: Articles ...
Sara E, Snow +2 more
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Ulipristal als noodanticonceptie?
Huisarts en wetenschap, 2016Vraagstelling Vorig voorjaar kwam er op het spreekuur een 18-jarige patiente nadat ze vier dagen daarvoor onbeschermd gemeenschap had gehad. Op thuisarts.nl stond (destijds) dat ze kon kiezen uit een koperspiraal of een nieuw soort morning-afterpil. Deze pil is tot vijf dagen na gemeenschap alleen op recept verkrijgbaar en kost rond de € 20.
José van der Velden +1 more
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Is Ulipristal Acetate a Liver Toxic Biomolecule? Toxicity assessment of ulipristal acetate
Revista de Chimie, 2018Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Its main functions are playing a key role in the development, differentiation, and normal functioning of female reproduction-related target tissues including the uterus (endometrium and myometrium)
Liana Ples +5 more
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