Results 11 to 20 of about 1,296 (168)

Progesterone Signaling and Uterine Fibroid Pathogenesis; Molecular Mechanisms and Potential Therapeutics

Cells, 2023
Uterine fibroids (UFs) are the most important benign neoplastic threat to women’s health worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy menstrual bleeding, pain, and infertility.
Mohamed Ali, Michał Ciebiera, Somayeh Vafaei, Samar Alkhrait, Hsin-Yuan Chen, Yi-Fen Chiang, Ko-Chieh Huang, Stepan Feduniw, Shih-Min Hsia, Ayman Al-Hendy   +9 more
doaj   +1 more source

A comparative prospective observational study on the use of ulipristal acetate versus mifepristone in reduction of the size of uterine leiomyoma

Asian Journal of Medical Sciences, 2022
Background: Fibroid or uterine leiomyoma is the most common benign tumor of the uterus in the reproductive age group and found in one out of every four women.
Lipika Ghosh , Abhijit Rakshit , Madhumita De   +2 more
doaj   +1 more source

Ulipristal Acetate in Adenomyosis

Gynecology and Minimally Invasive Therapy, 2022
Adenomyosis is defined as the invasion of the basal endometrium (stroma and glands) into the underlying myometrium. It may lead to abnormal uterine bleeding (AUB), pelvic pain, and infertility. The definitive treatment is hysterectomy. Some conservative measures have been used in patients willing to procreate.
Gonçalves-Henriques, Manuel, de Pinho, António, Freixo, Marília, Liz-Coelho, Maria, Castro, Fabiana, Ceschin, Nathan, Brandão, Pedro   +6 more
openaire   +2 more sources

Emergency Contraception Access and Counseling in Urban Pharmacies: A Comparison between States with and without Pharmacist Prescribing

Pharmacy, 2020
Pharmacists are often the primary source of emergency contraception (EC) access and patient information. This study aims to identify differences in pharmacist-reported EC access and counseling between states which do or do not permit pharmacist ...
Rebecca H. Stone, Sally Rafie, Dennia Ernest, Brielle Scutt   +3 more
doaj   +1 more source

The Cost-Effectiveness of Emergency Hormonal Contraception with Ulipristal Acetate versus Levonorgestrel for Minors in France.

PLoS ONE, 2015
ObjectiveTo evaluate the cost-effectiveness of ulipristal acetate and levonorgestrel in minors in France, and analyze whether it is worthwhile to provide ulipristal acetate to minors free of charge.MethodsThe cost-effectiveness of two emergency ...
Ramona Schmid
doaj   +1 more source

Hormonal assessment of patients of reproductive age with uterine myoma for surgical treatment

Медицинский совет, 2019
Aim: To assess the efficacy and safety of ulipristal acetate (UA) use in uterine myoma patients before surgical treatment. Material and methods: 78 patients of reproductive age with uterine bleeding and anemia, who underwent laparoscopic myomectomy, were
A. V. Kozachenko, Z. V. Revazova, L. V. Adamyan, T. A. Demura, N. V. Zaytsev   +4 more
doaj   +1 more source

Effect of a Selective Progesterone Receptor Modulator on Induction of Apoptosis in Uterine Fibroids In Vivo

International Journal of Endocrinology, 2012
Aim. To determine if hormonal treatment induces apoptosis in uterine fibroids. Methods. Immunohistochemical examination of fibroid tissue, using avidin-biotin complex and cleaved caspase-3 antibody for detecting apoptosis, was performed in premenopausal ...
Petr Horak, Michal Mara, Pavel Dundr, Kristyna Kubinova, David Kuzel, Robert Hudecek, Roman Chmel   +6 more
doaj   +1 more source

CLINICAL AND MORPHOLOGICAL RATIONALE FOR THE ULIPRISTAL ACETATE PRE-OPERATION TREATMENT BEFORE ORGANPRESERVING OPERATIONS IN MYOMAS UTERUS PATIENTS WITH THE INTRAUTERINE BLEEDING AND ANAEMIA

Медицинский совет, 2017
Objective: assessment of the feasibility and safety of the use of ulipristal acetate on the basis of the clinical and morphological study.Materials and methods: the study involved 78 women with leiomyoma, abundant menstruation and anemia.
A. V. Kozachenko, Z. V. Revazova, L. V. Adamyan, T. A. Demura   +3 more
doaj   +1 more source

Progesterone “against” progesterone. New links in the pathogenesis and future strategies in treatment of uterine fibroids

Репродуктивная эндокринология, 2018
Uterine myoma is a benign monoclonal solid tumor of the pelvis emanating from the smooth muscle tissue of the myometrium. Previously, it was considered that only hyperestrogens are the cause of the appearance and growth of fibromatosis.
А. Н. Григоренко
doaj   +1 more source

Long-term intermittent pharmacological therapy of uterine fibroids – a possibility to avoid hysterectomy and its negative consequences

Menopause Review, 2016
Uterine fibroids are found in almost 20-40% of women of reproductive age. For each woman an individualised treatment method should be applied because the hysterectomy procedure is not a good option in every case. The uterus is an organ necessary not only
Anita Olejek, Katarzyna Olszak-Wąsik, Anna Czerwinska-Bednarska   +2 more
doaj   +1 more source