Results 41 to 50 of about 575,882 (296)

A novel ultrafast-low-dose computed tomography protocol allows concomitant coronary artery evaluation and lung cancer screening [PDF]

, 2018
BACKGROUND:Cardiac computed tomography (CT) is often performed in patients who are at high risk for lung cancer in whom screening is currently recommended.
Bandiera, A, Barillari, P, Barillà, F, Gaudio, C, Mangieri, E, Paravati, V, Pellegrini, M, Pelliccia, F, Petriello, G, Tanzilli, A, Tanzilli, G   +10 more
core   +1 more source

Identifying Ultra-High Risk Smoldering Multiple Myeloma

Blood, 2018
Abstract Introduction Smoldering multiple myeloma (SMM) is an asymptomatic precursor stage to active multiple myeloma (MM), comprised by a heterogenous group of patients with varying rates of progression. While the overall yearly progression rate is 10% the first 5 years, some patients progress at a considerably higher ...
Theresia Akhlaghi, Even H Rustad, Venkata D Yellapantula, Neha Korde, Sham Mailankody, Nikoletta Lendvai, Alexander M. Lesokhin, Hani Hassoun, Sergio Giralt, Heather J. Landau, Eric L. Smith, Gunjan L. Shah, Michael Scordo, David J. Chung, Khalid Mezzi, Monica Khurana, Megan Braunlin, Winifred Werther, Ola Landgren, Malin Hultcrantz   +19 more
openaire   +1 more source

Prescription of antipsychotic medication to patients at ultra high risk of developing psychosis [PDF]

, 2009
Little is known about medication prescription in a naturalistic setting to patients at ultra high risk (UHR) of developing psychosis. Antipsychotic medication prescription to UHR patients is not recommended in clinical practice guidelines based on the ...
Broome, Cannon, Damiaan A.J.P. Denys, Don H. Linszen, Dorien H. Nieman, Hiske E. Becker, Johannessen, Kahn, Klosterkötter, Larsen, Lieuwe de Haan, Mark van der Gaag, McGlashan, McGlashan, McGorry, McGorry, Miller, Moncrieff, Morrison, Nelson, Peter M. Dingemans, Spitzer, Thérèse A. van Amelsvoort, Velthorst, Wera H. Rike, Yung, Yung, Yung   +27 more
core   +2 more sources

Relationship Between Polyunsaturated Fatty Acids and Psychopathology in the NEURAPRO Clinical Trial

Frontiers in Psychiatry, 2019
BackgroundDeficiencies in membrane polyunsaturated fatty acids (PUFA) such as omega-3 (n-3) fatty acids are thought to contribute to the pathophysiological processes underlying psychotic disorders.
Maximus Berger, Maximus Berger, Barnaby Nelson, Barnaby Nelson, Connie Markulev, Connie Markulev, Hok Pan Yuen, Hok Pan Yuen, Miriam R. Schäfer, Miriam R. Schäfer, Nilufar Mossaheb, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Todd W. Mitchell, Todd W. Mitchell, Barbara J. Meyer, Barbara J. Meyer, Andrew Thompson, Andrew Thompson, Alison Ruth Yung, Alison Ruth Yung, Alison Ruth Yung, Patrick D. McGorry, Patrick D. McGorry, G. Paul Amminger, G. Paul Amminger   +34 more
doaj   +1 more source

Cognitive-behavioural therapy role in the prevention of psychosis

European Psychiatry, 2021
Introduction About 30% of individuals in ultra-high risk (UHR) of psychosis develop overt psychosis within 3 years, and about 40% of those who don’t will keep experiencing ongoing attenuated psychotic symptoms and persistent functional disability ...
M. Pinho, D. Martins, S. Carvalho
doaj   +1 more source

A qualitative phenomenological analysis of the subjective experience and understanding of the at risk mental state

International Journal of Qualitative Studies on Health & Well-Being, 2017
Over recent years there has been a growing interest in identifying the early stages of psychosis. The At Risk Mental State (ARMS) is characteristic of the prodromal stages of psychosis and its identification gives rise to a number of clinical and ...
Benjamin Brew, Ciaran Shannon, Lesley Storey, Adrian Boyd, Ciaran Mulholland   +4 more
doaj   +1 more source

Defense Mechanisms in Adolescents at High Risk of Developing Psychosis: An Empirical Investigation

Research in Psychotherapy, 2020
Research within psychotherapy and psychopathology frameworks has been inspired by the central concept of defense mechanisms, which play a pivotal role in psychoanalysis.
Tommaso Boldrini, Gabriele Lo Buglio, Guido Giovanardi, Vittorio Lingiardi, Silvia Salcuni   +4 more
doaj   +1 more source

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy. [PDF]

, 2017
Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications.
Alva, Ajjai S, Brockman, Scott, Chinnaiyan, Arul M, Chugh, Rashmi, Feng, Felix Y, Grasso, Catherine S, Gursky, Amy, Haakenson, Christine, Henderson, James, Herman, Kirk, Hovelson, Daniel H, Husain, Hatim, Hussain, Maha H, Kamberov, Emmanuel, Kandarpa, Malathi, Kang, Qing, Krauss, John C, Langmore, John, Liu, Chia-Jen, Lonigro, Robert J, Mills, Ryan E, Morgan, Todd M, Quist, Michael J, Ramnath, Nithya, Robinson, Dan, Smith, David C, Talpaz, Moshe, Tesmer, Tim, Tewari, Muneesh, Tomlins, Scott A, Tuck, Missy, Wang, Yugang   +31 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Formal thought disorder in people at ultra-high risk of psychosis

BJPsych Open, 2017
Background Formal thought disorder is a cardinal feature of psychosis. However, the extent to which formal thought disorder is evident in ultra-high-risk individuals and whether it is linked to the progression ...
Arsime Demjaha, Sara Weinstein, Daniel Stahl, Fern Day, Lucia Valmaggia, Grazia Rutigliano, Andrea De Micheli, Paolo Fusar-Poli, Philip McGuire   +8 more
doaj   +1 more source