Results 81 to 90 of about 119,803 (296)

Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]

open access: yes, 2017
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and the CAS-Novonordisk Foundation, as well as grants from the ‘1000 talents’ recruitment program, and a ‘Great-wall professorship’ from ...
Jin, Wanzhu   +8 more
core   +2 more sources

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

open access: yesAdvanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang   +11 more
wiley   +1 more source

Label-free quantitative proteomic analysis of functional changes of goat milk whey proteins subject to heat treatments of ultra-high-temperature and the common low-temperature

open access: yesFood Chemistry: X
This work investigated the functional changes in whey proteins obtained from goat milk subject to various temperature treatments. Ultra-high temperature instantaneous sterilization (UHTIS) caused less damage than the common low-temperature, whereas spray-
Majida Al-Wraikat   +6 more
doaj   +1 more source

Melatonin concentration in cow’s milk and sources of its variation

open access: yesJournal of Applied Animal Research, 2019
The effects of weather/season (winter and summer), milk production (high and low), and milking time (night and day) on melatonin levels were evaluated. The melatonin in the milk from 30 individual cows, the bulk tank milk (BTM) from 16 farms, and ultra ...
Edilson Bruno Romanini   +5 more
doaj   +1 more source

Effect of Ultra-High-Temperature Treatment on Some Vitamins in Milk

open access: yesNihon Chikusan Gakkaiho, 1960
超高温処理法(135°C,2秒)がビタミンB1およびB2の破壊に及ぼす影響を,75°C,15分加熱処理法の場合と比較した.B1の定量は主としてHOUSTONの方法により,B2はKONらの方法によつた.得られた主要な結果は,次のとおりである.(1) 超高温処理法によるB1の平均破壊率は3.2%,また75°C,15分の加熱処理法によるそれは2.2%であつた.(2) B2の平均破壊率は,超高温処理法では5.3%,また75°C,15分の加熱処理法では4.2%であつた.すなわち超高温処理法のほうが,B1およびB2いずれの破壊率においても大であるが,両種の方法の間の差は僅少であるから,実用上,これらの方法の間には差異がないものと解しても差しつかえなかろう.
Taro NAGASAWA   +3 more
openaire   +2 more sources

Pilot study into milk haptoglobin as an indicator of udder health in heifers after calving [PDF]

open access: yes, 2018
Mastitis, inflammation of the mammary gland, is often caused by intramammary infection with bacterial organisms. It impacts on dairy cattle welfare, production, udder health and longevity in the herd.
Campbell, M.   +6 more
core   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

open access: yesAdvanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li   +9 more
wiley   +1 more source

Quality of ultra-high temperature treated chocolate milk manufactured in Bangladesh

open access: yesBangladesh Journal of Animal Science, 2015
Quality of ultra-high temperature (UHT) treated chocolate milk manufactured by different manufacturing companies of Bangladesh was evaluated. The milk samples were collected from retail shops of different markets supplied by three major dairy brands namely Aarong, Starship and Milkman.
MF Imam, MH Rashid, R Habib, MA Sabbir
openaire   +2 more sources

Fourier transform infrared spectroscopy analysis of physicochemical changes in UHT milk during accelerated storage [PDF]

open access: yes, 2017
The feasibility of using Fourier transform infrared spectroscopy (FTIR) to detect heat induced conformational rearrangements of proteins, protein-protein and protein-lipid interactions was studied with accelerated shelf-life protocols.
Apostolopoulos, Vasso   +5 more
core   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

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