Results 121 to 130 of about 1,298 (225)

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

A Novel Approach to Visualize and Quantify the Transient Air Infiltration/Exfiltration in Walk-in Coolers

open access: yes, 2018
Walk-in coolers are room-sized, insulated, and refrigerated compartments for food product storage. Walk-ins have areas equal or below 280 m2 (3,000 ft2), and are classified either as coolers operating above 0 degrees C (32 degrees F) (medium-temperature)
Kamensky, K.   +2 more
core  

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

open access: yesAdvanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang   +13 more
wiley   +1 more source

Application of Vacuum Insulated Panels in Commercial Service Cabinets

open access: yes, 2014
Published attempts to use VIPs (Vacuum Insulation Panels) to improve the thermal performance of cool boxes had found that VIPs do not yield their expected benefits, often only realising 2.5 to 3 times the improvement over PU (Polyurethane) rather than ...
Marques, C., Hammond, E.
core  

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

open access: yesAdvanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao   +12 more
wiley   +1 more source

Streamlining protocols for the establishment of a physical biobank of respiratory viruses in the Philippines. [PDF]

open access: yesJ Transl Med
Reyes-Haygood SJ   +7 more
europepmc   +1 more source

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