Results 251 to 260 of about 575,882 (298)

Locus of Control behavior in ultra-high risk patients.

Rivista di psichiatria, 2022
The term "Locus of Control" has been defined by Rotter (1954) as a general attitude regarding the nature of the causal relationship between one's behavior and its consequences. External Locus of Control Behavior represents an important factor of psychopathological vulnerability and can increase people's vulnerability to psychosis. Using the Craig Scale
Ribolsi, M, Albergo, G, Leonetti, F, Niolu, C, di Lazzaro, V, Siracusano, A, Di Lorenzo, G   +6 more
openaire   +3 more sources

Classifying ultra-high risk smoldering myeloma

Leukemia, 2014
Multiple myeloma (MM) always evolves from a precursor state, either monoclonal gammopathy of undetermined significance or smoldering MM (SMM).1, 2 These precursor states are defined by the absence of MM-related organ damage (‘CRAB’ features: hypercalcemia, renal failure, anemia and bone disease).3 SMM has a highly variable clinical behavior, where some
A J, Waxman, R, Mick, A L, Garfall, A, Cohen, D T, Vogl, E A, Stadtmauer, B M, Weiss   +6 more
openaire   +2 more sources

The Ultra High Risk Approach to Define Psychosis Risk

Current Pharmaceutical Design, 2012
Although prodromal symptoms of psychosis have long been recognized, the clinical management of psychotic disorders conventionally begins at the first episode of frank psychosis, and, until recently, the period immediately preceding the first episode received relatively little attention.
Yung, Alison R., Fusar-Poli, Paolo, Nelson, Barnaby   +2 more
openaire   +4 more sources

Prolonged Isotretinoin in Ultra High-Risk Neuroblastoma

Journal of Pediatric Hematology/Oncology, 2017
Patients with high-risk neuroblastoma remain a therapeutic challenge with significant numbers of patients failing to respond sufficiently to initial therapy. These patients with poor response to induction are considered as ultra high-risk and are in need of novel treatment strategies.
Thomas, Cash, Adina, Alazraki, Muna, Qayed, Howard M, Katzenstein   +3 more
openaire   +2 more sources

The challenge of defining “ultra‐high‐risk” neuroblastoma

Pediatric Blood & Cancer, 2018
AbstractGiven the biological and clinical heterogeneity of neuroblastoma, risk stratification is vital to determining appropriate treatment. Historically, most patients with high‐risk neuroblastoma (HR‐NBL) have been treated uniformly without further stratification.
Daniel A. Morgenstern, Rochelle Bagatell, Susan L. Cohn, Michael D. Hogarty, John M. Maris, Lucas Moreno, Julie R. Park, Andrew D. Pearson, Gudrun Schleiermacher, Dominique Valteau‐Couanet, Wendy B. London, Meredith S. Irwin   +11 more
openaire   +2 more sources

Risk stratification for treating people at ultra-high risk for psychosis: A cost-effectiveness analysis

Schizophrenia Research, 2023
People who are at ultra-high risk (UHR) for psychosis receive clinical care with the aim to prevent first-episode psychosis (FEP), regardless of the risk of conversion to psychosis. An economic model from the Canadian health system perspective was developed to evaluate the cost-effectiveness of treating all with UHR compared to risk stratification over
Ologundudu, Olajumoke M., Palaniyappan, Lena, Cipriano, Lauren E., Wijnen, Ben F.M., Anderson, Kelly K., Ali, Shehzad   +5 more
openaire   +3 more sources

Ultra High-Risk Myeloma

Hematology, 2010
Abstract Ultra high-risk myeloma can be defined as myeloma leading to death within 24 months. Despite tremendous improvements in the past decade (especially because of the availability of novel drugs such as thalidomide, bortezomib, and lenalidomide), these patients still represent 15% to 20% of the patients.
openaire   +2 more sources

Ultra High-risk Gestational Trophoblastic Neoplasia

Hematology/Oncology Clinics of North America
Ultra high-risk gestational trophoblastic neoplasia (GTN) refers to patients with World Health Organization prognostic risk scores of at least 13. The mortality risk for these patients averages 30%. Ultra high-risk GTN more frequently presents with higher tumor volume, liver and/or brain metastases, and very high human chorionic gonadotropin levels ...
Kevin M, Elias, Ross S, Berkowitz, Neil S, Horowitz   +2 more
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Understanding and Managing Ultra High-Risk Chronic Lymphocytic Leukemia

Hematology, 2010
AbstractModern treatment approaches such as chemoimmunotherapy (e.g., fludarabine/cyclophosphamide/rituximab or FCR) are highly effective in the majority of chronic lymphocytic leukemia (CLL) patients. However, there remains a small but challenging subgroup of patients who show ultra high-risk genetics (17p deletion, TP53 mutation) and/or poor response
Stephan, Stilgenbauer, Thorsten, Zenz
openaire   +2 more sources

Ultra-high-risk paradigm: lessons learnt and new directions

Evidence Based Mental Health, 2018
Within the embryonic early psychosis field in the early 1990s, the conceptualisation and definition of an at-risk or ultra-high-risk (UHR) mental state for psychosis was a breakthrough which transformed the clinical and research landscape in psychiatry.
Patrick D, McGorry, Cristina, Mei
openaire   +2 more sources