A critique of the “ultra‐high risk” and “transition” paradigm [PDF]
World Psychiatry, 2017 The transdiagnostic expression of psychotic experiences in common mental disorder (anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a small minority of people may indeed develop a clinical picture that meets criteria for schizophrenia.
van Os, Jim, Guloksuz, Sinan
openaire +2 more sources
Formal thought disorder in people at ultra-high risk of psychosis
BJPsych Open, 2017 Background Formal thought disorder is a cardinal feature of psychosis. However, the extent to which formal thought disorder is evident in ultra-high-risk individuals and whether it is linked to the progression ...
Arsime Demjaha +8 more
doaj +1 more source
Social cognition in adolescents at risk for psychosis: A 2-year follow-up study
European Psychiatry, 2021 Introduction Deficits in social cognition have been reported in people at ultra-high risk (UHR) of psychosis exclusively using socio-cognitive tasks and in adolescent and young adult mixed population.
L. Pelizza +7 more
doaj +1 more source
DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. [PDF]
, 2017 Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature.
Berry, Don +20 more
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Empiric treatment of pulmonary TB in the Xpert era: Correspondence of sputum culture, Xpert MTB/RIF, and clinical diagnoses. [PDF]
, 2019 BackgroundClinical tuberculosis diagnosis and empiric treatment have traditionally been common among patients with negative bacteriologic test results. Increasing availability of rapid molecular diagnostic tests, including Xpert MTB/RIF and the new Xpert
Cattamanchi, Adithya +12 more
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A novel ultrafast-low-dose computed tomography protocol allows concomitant coronary artery evaluation and lung cancer screening [PDF]
, 2018 BACKGROUND:Cardiac computed tomography (CT) is often performed in patients who are at high risk for lung cancer in whom screening is currently recommended.
Bandiera, A +10 more
core +1 more source
Prescription of antipsychotic medication to patients at ultra high risk of developing psychosis [PDF]
, 2009 Little is known about medication prescription in a naturalistic setting to patients at ultra high risk (UHR) of developing psychosis. Antipsychotic medication prescription to UHR patients is not recommended in clinical practice guidelines based on the ...
Broome +27 more
core +2 more sources
Identifying Ultra-High Risk Smoldering Multiple Myeloma
Blood, 2018 Abstract Introduction Smoldering multiple myeloma (SMM) is an asymptomatic precursor stage to active multiple myeloma (MM), comprised by a heterogenous group of patients with varying rates of progression. While the overall yearly progression rate is 10% the first 5 years, some patients progress at a considerably higher ...
Theresia Akhlaghi +19 more
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School Counselors’ Recognition of the Ultra-High Risk for Psychosis [PDF]
Psychiatry Investigation, 2018 The ability to identify students at ultra-high risk (UHR) for psychosis in school settings is crucial for enabling appropriate referral to a clinician and positive therapeutic results. The aim of this study was to examine school counselors' recognition of the diagnosis and appropriate treatment recommendations for students at UHR for psychosis.
Lee, Ju-Yeon +5 more
openaire +2 more sources
Shame and guilt in youth at ultra-high risk for psychosis
Comprehensive Psychiatry, 2021 Objective: Feelings of shame and guilt have rarely been investigated in people at ultra-high risk (UHR) for psychosis. We aimed to outline differences in shame and guilt in relation to empathy and theory of mind (ToM) in young people, particularly those ...
Hye Yoon Park +5 more
doaj +1 more source