A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang +12 more
wiley +1 more source
A Pollution Detection System for Plastic Ocean Waste Based on Energy-Harvesting Radio Transmitters. [PDF]
Beschastnyi V, Ostrikova D, Samouylov K.
europepmc +1 more source
Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li +8 more
wiley +1 more source
Sensing Platform Technologies of the Transient Electromagnetic Method for Urban Underground Space Detection: Challenges and Advances. [PDF]
Guo H, Gu Q, Xu J, Shi H, Bian L, Xu Z.
europepmc +1 more source
Stochastic Entanglement of Deterministic Origami Tentacles For Robust Robotic Grasping
This study introduces an origami tentacle gripper to robustly grasp objects‐in air, underwater, and even in orbital space‐by exploiting a synergy between local, deterministic deformation programming and global, stochastic entanglements. A single origami tentacle can be designed to coil with a simple tendon pull.
Alec Boron +4 more
wiley +1 more source
Synchronization enhanced force microscopy for clinical tumor tissue mechanical characterization. [PDF]
Song J +5 more
europepmc +1 more source
Self-Referenced and Wide-Range Tunable Microwave Frequency Measurement Using Period-One Oscillation and Spectral Gating. [PDF]
Yang Z, Liu Z, Dong W.
europepmc +1 more source
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He +9 more
wiley +1 more source
Design of a Multistable Cantilever Piezoelectric Vibration Energy Harvester with Nonlinear Force Customization. [PDF]
Luo E +5 more
europepmc +1 more source
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source

