Results 121 to 130 of about 68,271 (373)

Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

open access: yesAdvanced Science, EarlyView.
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang   +6 more
wiley   +1 more source

In vitro labeling of β-apolipoprotein with 3H or 14C and preliminary application to turnover studies

open access: yesJournal of Lipid Research, 1975
3-H- or 14C-labeled methyl groups were introduced into apolipoproteins of human and pig low density lipoproteins (LDL). 98% of the label was recovered in the apoprotein of radiomethylated LDL.
V.K. Murthy, T.C. Monchesky, G. Steiner
doaj  

Measuring compressibility in the optima AUC™ analytical ultracentrifuge

open access: yesEuropean Biophysics Journal, 2020
Marielle Stoutjesdyk   +3 more
semanticscholar   +1 more source

Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds

open access: yesAdvanced Science, EarlyView.
Selected plant‐type ferredoxins that lack their natural [2Fe‐2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, the light‐dependent H₂ evolution almost matches the H₂ production rates of the natural system.
Yiting She   +6 more
wiley   +1 more source

Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture

open access: yesScientific Reports, 2017
Extracellular vesicles (EVs) are involved in intercellular communication and affect processes including immune and antiviral responses. Blood serum, a common cell culture medium component, is replete with EVs and must be depleted prior to EV-related ...
Zhaohao Liao   +6 more
doaj   +1 more source

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

open access: yesAdvanced Science, EarlyView.
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang   +8 more
wiley   +1 more source

216 Jewish Hospital of St. Louis [PDF]

open access: yes, 1975
https://digitalcommons.wustl.edu/bjc_216/1131/thumbnail ...

core   +1 more source

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