Results 161 to 170 of about 70,242 (336)
SiMPull-POP: Quantification of Membrane Protein Assembly via Single Molecule Photobleaching. [PDF]
Schuck RJ +3 more
europepmc +1 more source
PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao +24 more
wiley +1 more source
Protocol for endolysosomal proteomics in goat atrial tissue using a refined density-gradient approach. [PDF]
Ayagama T +6 more
europepmc +1 more source
A novel strategy for in situ multiplexed miRNA analysis of plasma extracellular vesicles (EValarm) has been developed. EValarm enables straightforward detection of different extracellular vesicle miRNAs from plasma samples through systematic screening of liposome surface charges, without requiring complex pretreatment steps, and achieves satisfactory ...
Jing‐Yuan Ma +13 more
wiley +1 more source
Protocol for isolating and characterizing extracellular vesicles by ultracentrifugation from bone marrow-derived macrophages. [PDF]
Chen Y +8 more
europepmc +1 more source
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao +12 more
wiley +1 more source
Correction: Efficient methods of isolation and purification of extracellular vesicles. [PDF]
Kim T, Hong JW, Lee LP.
europepmc +1 more source
Structure of an innexin gap junction channel and cryo-EM sample preparation. [PDF]
Oshima A.
europepmc +1 more source
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena +11 more
wiley +1 more source

