Results 161 to 170 of about 68,271 (373)

Engineered Bacterial Outer Membrane Vesicles Hitchhiking on Neutrophils for Antibody Drug Delivery to Enhance Postoperative Immune Checkpoint Therapy

open access: yesAdvanced Science, EarlyView.
This study employs neutrophils for the precise delivery of anti‐CD47 antibodies, combined with bacterial outer membrane vesicles, to enhance macrophage phagocytic function in the tumor microenvironment. This approach effectively activates T‐cell anti‐tumor immune responses and significantly reduces the risk of postoperative tumor recurrence and ...
Meng Guan   +15 more
wiley   +1 more source

Sequential microultracentrifugation of lipoproteins in 100 microliters of serum.

open access: yesJournal of Lipid Research, 1990
A method is described for sequential separation of high density, very low density, and low density lipoproteins (HDL, VLDL, and LDL, respectively) from 100 microliters of serum, using an air-driven ultracentrifuge (Airfuge, Beckman).
I R Kupke, S Wörz-Zeugner
doaj  

Small Extracellular Vesicle-Derived Circular RNA hsa_circ_0007386 as a Biomarker for the Diagnosis of Pleural Mesothelioma

open access: yesCells
Pleural mesothelioma (PM) is a highly aggressive tumor that is caused by asbestos exposure and lacks effective therapeutic regimens. Current procedures for PM diagnosis are invasive and can take a long time to reach a definitive result.
Sareh Zhand   +5 more
doaj   +1 more source

Laser light scattering and ultracentrifuge studies on sheep liver cytosolic aldehyde dehydrogenase : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University, New Zealand [PDF]

open access: yes, 1995
The techniques of laser light scattering and ultracentrifugation were used to investigate the association - dissociation behaviour of sheep liver cytosolic aldehyde dehydrogenase. Diffusion and sedimentation coefficients were obtained by these techniques.
Harvey, Jacqueline Jean
core  

STUDIES ON THE FINE STRUCTURE OF ULTRACENTRIFUGED SPINAL GANGLION CELLS [PDF]

open access: bronze, 1960
H. W. Beams   +3 more
openalex   +1 more source

Tβ4‐Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A separable microneedle patch is designed for Tβ4–modified ADSC‐derived extracellular vesicles delivery. The overexpressed Tβ4 released from the microneedles can mitigate cellular senescence and promote wound healing via the PTEN/PI3K/AKT pathway, offering a promising approach for diabetic wound treatment. This bioengineered therapeutic system serve as
Youjun Ding   +7 more
wiley   +1 more source

Enhancing Chemotherapy‐Related Immune Responses via Bioorthogonal Metabolic Engineering‐Driven Tumor Exosomes Elimination

open access: yesAdvanced Science, EarlyView.
In this work, a novel strategy named bioorthogonal reaction‐driven exosome elimination (Biordee) strategy was developed to inhibit chemotherapy‐associated breast cancer metastasis and enhance the immune response. Biordee possessed the capacity of in‐situ editing tumor‐derived exosomes (TExo) with IgG Fc and promoted macrophage phagocytosis of ...
Wentao Zhang   +6 more
wiley   +1 more source

Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon

open access: yesAdvanced Science, EarlyView.
This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu   +8 more
wiley   +1 more source

Structures of Polyhydroxyalkanoate Synthase PhaC from Aeromonas caviae, Producing Biodegradable Plastics

open access: yesAngewandte Chemie, EarlyView.
PHA synthase (PhaC) is the key enzyme in the polymerization of a biodegradable plastic—polyhydroxyalkanoate (PHA). Structures of full‐length PhaC reveal three key regions essential for substrate specificity and polymerization. Additionally, this study also highlights the critical role of N‐domain‐dependent dimerization in PhaC activity.
Min Fey Chek   +5 more
wiley   +2 more sources

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