Results 201 to 210 of about 68,271 (373)

Blocking ITGA5 potentiates the efficacy of anti‐PD‐1 therapy on glioblastoma by remodeling tumor‐associated macrophages

open access: yesCancer Communications, EarlyView.
Abstract Background Glioblastoma (GBM) is largely refractory to antibodies against programmed cell death 1 (anti‐PD‐1) therapy. Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM.
Rongrong Zhao   +11 more
wiley   +1 more source

Isolation and Biophysical Characterization of Extracellular Vesicles from Hairy Root Cultures. [PDF]

open access: yesBio Protoc
Conte M   +6 more
europepmc   +1 more source

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

open access: yesCancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu   +12 more
wiley   +1 more source

Respiratory extracellular vesicle isolation optimization through proteomic profiling of equine samples and identification of candidates for cell-of-origin studies. [PDF]

open access: yesPLoS One
Hickman E   +12 more
europepmc   +1 more source

Characterization of DnaB‐DnaG Interaction in M. tuberculosis using a SAXS‐Based Dissociation Assay

open access: yesChemBioChem, Accepted Article.
We studied the complex interactions between helicase and primase, two key components of the replisome involved in DNA replication in Mycobacterium tuberculosis. Utilizing purified, complementary domains of these proteins, we employed a surface plasmon resonance (SPR) analysis and a cross‐linking assay to characterize their binding dynamics.
Barak Akabayov, Adi Dayan, Stefan Ilic
wiley   +1 more source

Protocol for isolating extracellular vesicles from alveolar macrophages phagocytosing MRSA in vitro cell culture models. [PDF]

open access: yesSTAR Protoc
Bai S   +10 more
europepmc   +1 more source

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