Results 51 to 60 of about 68,271 (373)

The uses of the ultracentrifuge [PDF]

open access: yesJournal of Chemical Education, 1955
This award address examines the theory and applications of the ultracentrifuge to sedimentation measurements. Presented as the Kendall Award address at the 127th ACS Meeting, Cincinnati, March, 1955.
openaire   +2 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Isolation of Extracellular Vesicles Derived from Mesenchymal Stromal Cells by Ultracentrifugation

open access: yesBio-Protocol, 2020
Extracellular vesicles (EVs) are a heterogeneous group of membranous vesicles that differ on their biogenesis and release pathways, such as exosomes, microvesicles and apoptotic bodies.
María José Ramírez-Bajo   +4 more
doaj   +1 more source

Assembly, Loading, and Alignment of an Analytical Ultracentrifuge Sample Cell

open access: yesJournal of Visualized Experiments, 2009
The analytical ultracentrifuge (AUC) is a powerful biophysical tool that allows us to record macromolecular sedimentation profiles during high speed centrifugation.
Andrea Balbo   +3 more
semanticscholar   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu   +12 more
wiley   +1 more source

A novel three step protocol to isolate extracellular vesicles from plasma or cell culture medium with both high yield and purity

open access: yesJournal of Extracellular Vesicles, 2020
Extracellular vesicles (EV) are membrane encapsulated nanoparticles that can function in intercellular communication, and their presence in biofluids can be indicative for (patho)physiological conditions.
Xiaogang Zhang   +4 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Microsomal nucleoprotein particles from pea seedlings [PDF]

open access: yes, 1956
Ultracentrifugal analysis of an extract of pea epicotyls, previously freed of debris and larger particles by centrifugation at 40,000 g for 10 minutes, has revealed the presence of a major component which possesses a sedimentation coefficient of 74 S ...
Bonner, James   +2 more
core  

Thermal bulk polymerization of cholesteryl acrylate [PDF]

open access: yes, 1971
The thermal bulk polymerization of cholesteryl acrylate was carried out in the solid phase, the mesomorphic phase, and the liquid phase to study the effect of monomer ordering on polymerization rate and polymer properties.
Bantjes, A.   +3 more
core   +2 more sources

Performance of a fast fiber based UV/Vis multiwavelength detector for the analytical ultracentrifuge

open access: yesColloid and Polymer Science, 2007
The optical setup and the performance of a prototype UV/Vis multiwavelength analytical ultracentrifuge (MWL-AUC) is described and compared to the commercially available Optima XL-A from Beckman Coulter.
H. Strauss   +5 more
semanticscholar   +1 more source

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