Results 221 to 230 of about 226,162 (380)

A case study showing the role of hydrophobicity variants and other enriched mAb proteoforms on filterability through a virus filter with productivity improvement measures

open access: yesBiotechnology Progress, EarlyView.
Abstract A rapid assessment of manufacturability for drug candidates is crucial for advancing a prospective biotherapeutic from a candidate to a bulk drug substance. A lot‐to‐lot approach to manufacturability is adopted where each biologic batch is assessed for manufacturability as a bulk, unfractionated pool.
Solomon Isu   +6 more
wiley   +1 more source

Multiscale Modelling of Protein Fouling in Ultrafiltration

open access: diamond, 2012
Francesca Paone   +3 more
openalex   +1 more source

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

open access: yesBiotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal   +5 more
wiley   +1 more source

Synthesizing polyethersulphone membranes with hybrid iron/nickel nanoparticles for dyes removal: An efficient biogenesis approach

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Industrial wastewater contamination by azo dyes poses a significant environmental challenge. This study reports the green synthesis of bimetallic iron/nickel (Fe/Ni) nanoparticles using moringa leaf extract, which acted as both a reducing and capping agent, and their incorporation into polyethersulphone (PES) membranes to produce eco‐friendly ...
Qusay A. Almajras   +7 more
wiley   +1 more source

Late-onset polyvinylpyrrolidone allergy in a long-term hemodialysis patient: a case report of dialysis hypotension and gastrointestinal symptoms. [PDF]

open access: yesCEN Case Rep
Narita T   +10 more
europepmc   +1 more source

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