Results 31 to 40 of about 11,298 (262)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Optimization of ultrasonic rolling parameters act on thread root and its influence on the fatigue life of bolts [PDF]

ITM Web of Conferences
Due to the large stress concentration at the root of the external thread, fatigue failure is apt to occur when subjected to alternating loads. In present study, to improve the fatigue resistance of threaded components, an ultrasonic rolling method was ...
Liu Xuanyu, Li Lei, Kang Haonan, Zheng Xiaodong   +3 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Study on ultrasonic evaluation of connection state and service performance of resistance projection welding joints

Discover Applied Sciences
Fatigue failure of welded joints is a performance factor of structural parts under dynamic load, and the effective evaluation of its life is always the key to the service ability of structures.
Zhenzhen Duan, Xueshan Zhao, Guanghao Zhou, Kunning Jia, Xiaopeng Gu, Ting Ma   +5 more
doaj   +1 more source

Very High Cycle Fatigue Behavior of Austenitic Stainless Steels with Different Surface Morphologies

Metals, 2022
The fatigue behavior of the two austenitic stainless steels AISI 904L and AISI 347 with different surface morphologies, (i) conventionally turned and finally polished, (ii) cryogenic turned using CO2 snow, as well as (iii) cryogenic turned and finally ...
Marek Smaga, Annika Boemke, Dietmar Eifler, Tilmann Beck   +3 more
doaj   +1 more source

Fatigue deformation of 1050 aluminum in ultrasonic fatigue testing.

Journal of Japan Institute of Light Metals, 1995
Ultrasonic fatigue tests have been performed on commercial 1050 aluminum. Internal friction (Q-1) has been measured during fatigue tests and as a function of strain amplitude (e). It is shown that more than 109 cycles test is necessary in order to determine the fatigue limit. Q-1 versus e curves have the inflection points at particular strain amplitude
YAMAMOTO, Atsushi, MAEDA, Morihiko, TSUBAKINO, Harushige, IMANAKA, Takuichi, SUETSUGU, Jun   +4 more
openaire   +1 more source

ULTRASONIC ATTENUATION IN STEELS DURING FATIGUE [PDF]

Le Journal de Physique Colloques, 1985
The change of ultrasonic attenuation Ɗα as a function of fatigue cycle number n correlates well with the length of fatigue crack. A depinning model of dislocations with kinks is suggested to interpret the experimental results.
Zhengliang, Pan, Guangyi, Li
openaire   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Mechanistic Model of Fatigue in Ultrasonic Assisted Machining

Materials
Anti-fatigue design in the machining process of aviation material requires advanced processes to enhance the surface integrity and a holistic model which can optimize the process aiming at maximum fatigue life. In the present study, the axial ultrasonic assisted milling process was utilized to machine the Inconel 718 while the process executes the ...
Reza Teimouri, Marcin Grabowski
openaire   +2 more sources

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source