Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang +14 more
wiley +1 more source
Retropharyngeal Internal Carotid Artery Presenting as Chronic Otalgia and Throat Pain Mimicking Laryngopharyngeal Reflux: A Case Report. [PDF]
Rivero K +5 more
europepmc +1 more source
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Comment on: "Ultrasound of the Cheek: Are We Ready for Clinical Adoption?" [PDF]
Munive AC +3 more
europepmc +1 more source
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu +13 more
wiley +1 more source
Can improving your aerobic fitness negate the immediate vascular consequences of prolonged sitting? [PDF]
Courish MK, O'Brien MW.
europepmc +1 more source
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Intravascular Ultrasound (IVUS)-Guided Endovascular Treatment of Severe Left Subclavian Artery Stenosis in a Patient With High-Risk Post-Coronary Artery Bypass Grafting Surgery. [PDF]
Tedla A +4 more
europepmc +1 more source
Ultrasound-guided musculoskeletal interventions and professional boundaries: an international expert opinion. [PDF]
Abdulsalam AJ +19 more
europepmc +1 more source
Pediatric emergency department point-of-care ultrasound diagnosis of unprovoked iliofemoral deep vein thrombosis in an adolescent: A case report. [PDF]
Elosiuba E +7 more
europepmc +1 more source

