Results 251 to 260 of about 47,503 (338)

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

open access: yesAdvanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang   +5 more
wiley   +1 more source

Mechanisms and Therapeutic Strategies for Minority Cell‐Induced Paclitaxel Resistance and Tumor Progression Mediated by Mechanical Forces

open access: yesAdvanced Science, EarlyView.
This study provides new perspectives into the interactions between mechanical forces and cellular dynamics within the tumor microenvironment, particularly elucidating how minority Paclitaxel‐resistant cancer cells (MRCs) promote tumor progression and treatment resistance through mechanical forces and also providing effective treatment strategies for ...
Xueyan Feng   +12 more
wiley   +1 more source

Diagnosis and Management of Inadvertent Iliac Vein Injury During Structural Heart Interventions. [PDF]

open access: yesJACC Case Rep
Sava RI   +5 more
europepmc   +1 more source

Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du   +21 more
wiley   +1 more source

Which localization method is optimal in ESWL: fluoroscopy or ultrasonography? [PDF]

open access: yesBMC Urol
Baba D   +7 more
europepmc   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

open access: yesAdvanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang   +4 more
wiley   +1 more source

Robustly Repeatable, Permeable, and Multi‐Axially Stretchable, Adhesive Bioelectronics With Super‐adaptive Conductive Suction Cups for Continuously Deformable Biosurfaces

open access: yesAdvanced Science, EarlyView.
It is presented bioelectronics that exhibit exceptional adaptability to dynamic skin surfaces through an integrated structural and material design. These omnidirectionally stretchable, skin‐compliant, mechanically robust, and permeably biocompatible kirigami‐based devices minimize skin irritation and conductivity loss and offer new insights for the ...
Gyun Ro Kang   +7 more
wiley   +1 more source

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