Results 61 to 70 of about 467,503 (346)

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Noninvasive Assessment of Tumor Histological Grade in Invasive Breast Carcinoma Based on Ultrasound Radiomics and Clinical Characteristics: A Multicenter Study

Technology in Cancer Research & Treatment
Rationale and Objectives: We aimed to develop and validate prediction models for histological grade of invasive breast carcinoma (BC) based on ultrasound radiomics features and clinical characteristics.
Lifang Ge MD, Jiangfeng Wu MD, Yun Jin MD, Dong Xu MD, Zhengping Wang MD   +4 more
doaj   +1 more source

Feasiblity Study on the Longitudinal Section of the Fetal Esophagus by Prenatal Ultrasound between 21 and 23 Gestational Weeks

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: Prenatal esophageal atresia (EA) diagnosis may improve outcomes by optimizing prenatal and postnatal care. This study evaluated the feasibility of direct antenatal visualization of normal longitudinal esophageal sections using two-dimensional
Xiulan Chen, Yongsheng Zhu, Ning Zhou, Li Ma, Mingfen Xu, Siyao Zhong   +5 more
doaj   +1 more source

Transcranial Doppler ultrasonography in neurological surgery and neurocritical care.

Neurosurgical Focus, 2019
Transcranial Doppler (TCD) ultrasonography is an inexpensive, noninvasive means of measuring blood flow within the arteries of the brain. In this review, the authors outline the technology underlying TCD ultrasonography and describe its uses in patients ...
Robert H. Bonow, Christopher C. Young, D. Bass, A. Moore, M. Levitt   +4 more
semanticscholar   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Influence of lesion size on shear wave elastography in the diagnosis of benign and malignant thyroid nodules

Scientific Reports, 2021
In shear wave elastography (SWE) studies, the optimal cutoff value of Young’s modulus for the diagnosis of benign and malignant thyroid nodules varies greatly, which affects the clinical application of the method.
Huizhan Li, Chunsong Kang, Jiping Xue, Liwei Jing, Junwang Miao   +4 more
doaj   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

AAPM medical physics practice guideline 13.a: HDR brachytherapy, part B

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The goal of this report is to assist the clinical medical physicist in assuring that key quality standards and practice considerations are met to ensure safe, reliable, and reproducible high dose rate (HDR) brachytherapy (BT) treatment. This guideline has been developed to provide appropriate minimum standards for such services.
Susan L. Richardson, Arjit K. Baghwala, Gil'ad N. Cohen, Claire Dempsey, Bruce Libby, Christopher S. Melhus, Robin A. Miller, Daniel J. Scanderbeg, Samantha J. Simiele   +8 more
wiley   +1 more source

Accuracy and reproducibility of a single‐pose image‐to‐robot registration method for mobile C‐arm cone beam CT guided histotripsy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Histotripsy is a focal tumor therapy that utilizes focused ultrasound (US) to mechanically destroy tissue. To overcome visualization limitations of diagnostic US‐guidance, C‐arm cone beam CT (CBCT)‐guided histotripsy is being developed, for which a mobile C‐arm could increase accessibility. CBCT‐guided histotripsy uses a phantom with a
Grace M. Minesinger, Paul F. Laeseke, Katrina L. Falk, Claire E. Hennen, Michael A. Speidel, Martin G. Wagner   +5 more
wiley   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source