Results 41 to 50 of about 1,845,177 (362)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Ultrasound Neuromodulation: A Review of Results, Mechanisms and Safety

Ultrasound in Medicine and Biology, 2019
Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US) is delivered to nervous system tissue, resulting in transient modulation of neural activity.
Joseph Blackmore, Shamit Shrivastava, J. Sallet, C. Butler, R. Cleveland   +4 more
semanticscholar   +1 more source

Recommendations for the Assessment of Carotid Arterial Plaque by Ultrasound for the Characterization of Atherosclerosis and Evaluation of Cardiovascular Risk: From the American Society of Echocardiography.

Journal of the American Society of Echocardiography, 2020
Atherosclerotic plaque detection by carotid ultrasound provides cardiovascular disease risk stratification. The advantages and disadvantages of two-dimensional (2D) and three-dimensional (3D) ultrasound methods for carotid arterial plaque quantification ...
A. Johri, Vijay Nambi, T. Naqvi, S. Feinstein, E. Kim, Margaret M. Park, H. Becher, H. Sillesen   +7 more
semanticscholar   +1 more source

Ovaidan Ultrasound Image Enhancement By Pseudocolouring. [PDF]

, 2004
Image processing may be employed on ovarian ultrasound images to assist doctors in diagnostic analysis. The gray levels of ovarian images are usually concentrated at the zero end of the spectrum ,making the image too low in contrast and too dark for the ...
Mashor, Mohd Yusoff, Ngah, Umi Kalthum, Saidin, Nafiza   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

Nature Communications, 2018
Magnetic resonance-guided focused ultrasound in combination with intravenously injected microbubbles has been shown to transiently open the blood–brain barrier, and reduce beta-amyloid and tau pathology in animal models of Alzheimer’s disease.
N. Lipsman, Y. Meng, A. Bethune, Yuexi Huang, B. Lam, M. Masellis, N. Herrmann, C. Heyn, I. Aubert, A. Boutet, Gwenn S. Smith, K. Hynynen, S. Black   +12 more
semanticscholar   +1 more source

WHOLE BREAST LESION DETECTION USING NAIVE BAYES CLASSIFIER FOR PORTABLE ULTRASOUND

, 2014
In recent years, portable PC-based ultrasound (US) imaging systems developed by some companies can provide an integrated computer environment for computer-aided diagnosis and detection applications.
Yang, Min-Chun;Huang, Chiun-Sheng;Chen, Jeon-Hor;Chang, Ruey-Feng, 黃俊升   +1 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Understanding the effects of obstetrical ultrasound [PDF]

, 1999
Plan BUltrasound has revolutionized the practice of obstetrics and significantly influenced the way society regards the fetus in utero. This study views the value of the obstetrical ultrasound in terms of human phenomenon.
Durbin, Sharon A.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source