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Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
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Advanced Science, EarlyView.In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun +15 more
wiley +1 more source
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Ultrasound contrast agents: A review
Ultrasound in Medicine and Biology, 1994During the past 25 years, many attempts have been made to establish effective ultrasound contrast agents for both cardiac and noncardiac applications. The ideal ultrasound contrast agent would be: (a) nontoxic; (b) injectable intravenously; (c) capable of passing through the pulmonary, cardiac and capillary circulations; and (d) stable for ...
Flemming Forsberg +2 more
exaly +3 more sources
Response of contrast agents to ultrasound
Advanced Drug Delivery Reviews, 2008Microbubbles are used as ultrasonic contrast agents that enhance the ultrasound signals of the vascular bed. The recent development of site-targeted microbubbles opened up the possibility for molecular imaging as well as localised drug and gene delivery.
Vassilis Sboros
exaly +3 more sources
Ultrabubble: A Laminated Ultrasound Contrast Agent with Narrow Size Range
Advanced Materials, 2009 A laminated shell microcapsule is described resisting aggregation and withstanding ultrasound destruction, showing a good backscatter signal, as shown in the figure. Templated synthesis produces versatile monodisperse capsules <3 mu m, with ultrasound-
Robert J. Eckersley, Elizabeth A H Hall
exaly +2 more sources
Safety of ultrasound contrast agents
European Radiology, 2005The use of ultrasound contrast agents has increased over recent years. The Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) decided to review the safety of ultrasound contrast agents in humans and to draw up guidelines. A comprehensive literature search and review was carried out.
Henrik S Thomsen +2 more
exaly +3 more sources
Der Radiologe, 2004
Ultrasound contrast agents consist of tiny gas bubbles encapsulated by a stabilising membrane or shell. When combined with recent contrast-specific ultrasound techniques, they provide substantial enhancement of vessels and solid organs. The clinical use and the diagnostic value of ultrasound contrast agents are in principle comparable to those of ...
T, Albrecht, J, Hohmann
openaire +3 more sources
Ultrasound contrast agents consist of tiny gas bubbles encapsulated by a stabilising membrane or shell. When combined with recent contrast-specific ultrasound techniques, they provide substantial enhancement of vessels and solid organs. The clinical use and the diagnostic value of ultrasound contrast agents are in principle comparable to those of ...
T, Albrecht, J, Hohmann
openaire +3 more sources
Contrast Agents in diagnostic ultrasound
Ultrasound in Medicine & Biology, 1989We review the field of contrast agents in diagnostic ultrasound. The progress in the development of various classes of contrast agents such as free and encapsulated gas bubbles, colloidal suspensions, emulsions, and aqueous solutions is described. The mechanisms for production of backscatter contrast, as well as attenuation contrast and speed of sound ...
J, Ophir, K J, Parker
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Ultrasound contrast agents for echocardiography
Drugs of Today, 2000There is a need to monitor perfusion of the microcirculation in patients with minimal invasive approaches. The recent development of ultrasound contrast agents may open such an opportunity and permit to visualize online perfusion of cardiac muscle and other organs.
T, Yasu, G W, Schmid-Schönbein
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