Results 51 to 60 of about 21,910 (284)

High-resolution acoustic mapping of tunable gelatin-based phantoms for ultrasound tissue characterization

Frontiers in Bioengineering and Biotechnology
Background: The choice of gelatin as the phantom material is underpinned by several key advantages it offers over other materials in the context of ultrasonic applications.
Heba M. Badawe, Petra Raad, Massoud L. Khraiche   +2 more
doaj   +1 more source

Overcoming the acoustic diffraction limit in photoacoustic imaging by localization of flowing absorbers

, 2017
The resolution of photoacoustic imaging deep inside scattering media is limited by the acoustic diffraction limit. In this work, taking inspiration from super-resolution imaging techniques developed to beat the optical diffraction limit, we demonstrate ...
Arnal, Bastien, Bossy, Emmanuel, Vilov, Sergey   +2 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Evaluation of physical properties and image quality of a breast tissue phantom with glycerol-enhanced polyvinyl chloride plastisol for ultrasound imaging [PDF]

Ultrasonography
Purpose This study aimed to fabricate and evaluate breast tissue-equivalent phantoms with varying glycerol concentrations, focusing on their physical properties (density, elasticity, and acoustic parameters) and ultrasound image quality metrics ...
Aditya Prayugo Hariyanto, Anggraini Dwi Sensusiati, Suprijanto, Mohamed Aminah, Sook Sam Leong, Freddy Haryanto, Kwan Hoong Ng, Endarko   +7 more
doaj   +1 more source

The impact of geometry, intramural friction, and pressure on the antegrade longitudinal motion of the arterial wall: A phantom and finite element study

Physiological Reports, 2023
Longitudinal motion of the carotid arterial wall, as measured with ultrasound, has shown promise as an indicator of vascular health. The underlying mechanisms are however not fully understood.
Sandra Sjöstrand, Alice Widerström, Ingrid Svensson, Patrick Segers, Tobias Erlöv, Åsa Rydén Ahlgren, Magnus Cinthio   +6 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Application of additive manufacturing for the adaptive design of ultrasound phantoms

Frontiers in Physics
IntroductionThe image formation process of conventional pulse-echo Ultrasound mainly uses the backscattered amplitude and assumes constant attenuation and speed of sound in the penetrated media.
Lukas Zalka, Lukas Zalka, Johannes Köhrer, Johannes Köhrer, Chatsuda Songsaeng, Chatsuda Songsaeng, Peter Homolka, Christian Kollmann, Johann Hummel, Johann Hummel, Michael Figl, Michael Figl   +11 more
doaj   +1 more source

A multi-angle plane wave imaging approach for high frequency 2D flow visualization in small animals: simulation study in the murine arterial system [PDF]

, 2014
To preclinically investigate the role of hemodynamics in atherogenesis, mouse models are particularly useful due to the rapid disease development. As such, murine blood flow visualization has become an important tool, with current US systems equipped ...
Ekroll, Ingvild, Lovstakken, Lasse, Segers, Patrick, Shcherbakova, Darya, Swillens, Abigail, Trachet, Bram   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source