Results 221 to 230 of about 177,865 (310)

Disruption of Fructose 1,6-Bisphosphatase 2 Proximity to MIC60 Correlates with Mitochondrial Ultrastructural Changes. [PDF]

Cells
Pietras Ł, Migocka-Patrzałek M, Budziak B, Rakus D, Gizak A.   +4 more
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Correction: TRPV1 deletion in male mice alters cardiomyocyte ultrastructure without affecting baseline cardiac function. [PDF]

Sci Rep
Tessier N, Païta L, Chouabe C, Thibault H, Melka M, Ducrozet M, Al-Mawla R, Harisseh R, Léon C, Augeul L, Dupré-Aucouturier S, Bidaux G, Ovize M, Van Coppenolle F, Ducreux S.   +14 more
europepmc   +1 more source

Tumor‐Derived Exosomal piR‐hsa‐28212 Promotes Lymphatic Metastasis in Breast Cancer

Cancer Science, EarlyView.
Breast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Yafen Wang, Tianli Zhang, Xue Kong, Yao Tong, Yanru Li, Xiangjun Dong, Chuanxin Wang, Juan Li   +7 more
wiley   +1 more source

Correction: Kim et al. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation During the Laxative Effect of <i>Asparagus cochinchinensis</i> in Loperamide-Induced Constipation of SD Rats. <i>Int. J. Mol. Sci.</i> 2019, <i>20</i>, 946. [PDF]

Int J Mol Sci
Kim JE, Park JW, Kang MJ, Choi HJ, Bae SJ, Choi YS, Lee YJ, Lee HS, Hong JT, Hwang DY.   +9 more
europepmc   +1 more source

Biallelic Truncating Variant in LRGUK Is Associated With Severe Multiple Morphological Abnormalities of the Sperm Flagella and Sperm Nuclear Defects in Humans

Clinical Genetics, EarlyView.
A homozygous truncating variant in LRGUK results in loss of the LRGUK protein and causes multiple morphological abnormalities of the flagella (MMAF), disrupted axonemal architecture, central pair defects, abnormal chromatin organization, and severe male infertility, establishing LRGUK as a novel human infertility gene.
Wiâme Mokkedem, Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Célia Tebbakh, Nicolas Thierry‐Mieg, Marie Bidart, Antonella Migliaccio, Rosanna Chianese, Christophe Arnoult, Raoudha Zouari, Zine‐Eddine Kherraf, Pierre F. Ray, Guillaume Martinez, Charles Coutton   +14 more
wiley   +1 more source

Preliminary ultrastructural analysis suggests phenotype-specific myofiber alterations in idiopathic inflammatory myopathies. [PDF]

Sci Rep
Aguilar-Vazquez A, Juarez-Gomez C, Gonzalez-Gauna E, Medrano-Ramirez G, Vargas-Cañas S, Vargas-Guerrero A, Gutiérrez-Hernández JM, Toriz G, Gomez-Rios CA, Medina-Preciado JD, Chavarria-Avila E, Martin-Marquez BT, Pizano-Martinez O, Martinez-Garcia EA, Perez-Vazquez F, Sandoval-Garcia F, Salazar-Paramo M, Rubio-Arellano ED, Becerra-Jimenez J, Garcia-Ordoñez G, Gaspar-Ruiz A, Ramos-Hernandez A, Cabrera-Lopez M, Llamas-Garcia A, Vazquez-Del Mercado M.   +24 more
europepmc   +1 more source

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

Cell Proliferation, EarlyView.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang, Yuan‐Tao Qiu, Jing‐Yue Cao, Yi‐Feng Huang, Ye‐Lin Lan, Yu‐Li Zhao, Fu Wu, Chen‐Long Wang, Guo‐Run Tang, Jing‐Yun Ji, Zhang Zhang, Guan‐Zheng Luo   +11 more
wiley   +1 more source

Extracellular vesicle-mediated signalling in human rescue <i>in vitro</i> maturation: methodological and mechanistic considerations. [PDF]

Hum Reprod Open
Sun X.
europepmc   +1 more source

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

The FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal, Samara de Oliveira Pimentel, Bruno da Costa Rodrigues, Mauro Sérgio Gonçalves Pavão, Rodrigo Nunes da Fonseca, Cintia Monteiro de Barros   +5 more
wiley   +1 more source