Results 141 to 150 of about 221,628 (302)

Response of rat tracheal epithelium to ozone and oxygen exposure in vitro. [PDF]

open access: yes, 1990
Although ozone-induced epithelial injury in vivo has been morphologically characterized, effects of gaseous oxidants on respiratory epithelium in organ culture, where tissue organization is maintained but systemic influences are eliminated, have not been
Nikula, KJ, Wilson, DW
core  

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

open access: yesJournal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang   +4 more
wiley   +1 more source

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu   +8 more
wiley   +1 more source

Image Analysis Platform for Comprehensive Quantification of Extracellular Vesicle Morphology

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐encapsulated nanoparticles with key roles in cell biology and growing importance in biomedicine. However, EVs are challenging to characterize because they are highly heterogeneous. Single EV analysis methods are valuable tools for addressing this challenge.
Alexander Spark   +7 more
wiley   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira   +8 more
wiley   +1 more source

Structure of cytoplasmic 80S and mitochondrial 60S ribosomes from Locusta migratoria [PDF]

open access: yes, 1974
Goodchild, D. J.   +4 more
core   +1 more source

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