Results 151 to 160 of about 83,020 (238)

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

open access: yesVIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li   +10 more
wiley   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

open access: yesVIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li   +5 more
wiley   +1 more source

Comparative Outcomes of Two Non‐Crosslinked Porcine Acellular Dermal Matrices in Complex Abdominal Wall Reconstruction: A Randomized Controlled Trial and an Observational Cohort Study

open access: yesWorld Journal of Surgery, EarlyView.
Biologic mesh has historically been used for ventral hernia repairs (VHR) in contaminated fields in an off‐label fashion due to early evidence suggesting that they may be able to withstand these conditions more favorably than synthetic mesh. This study aims to compare outcomes of two non‐crosslinked porcine acellular dermal matrices—XenMatrix (Bard ...
Abdulaziz Elemosho   +7 more
wiley   +1 more source

Ultrastructural Synaptic Differences in the Central Inferior Colliculus in the 3xTG Mouse Across Three Disease Stages. [PDF]

open access: yesJ Comp Neurol
Mellott JG   +8 more
europepmc   +1 more source

Critical point drying of brain tissue for X‐ray phase‐contrast imaging

open access: yesJournal of Synchrotron Radiation, EarlyView.
X‐ray phase contrast tomography can efficiently image brain tissue at subcellular resolution. Critical point drying allows a gentle replacement of interstitial material by air, enhancing X‐ray phase contrast of the ultrastructural features.X‐ray phase‐contrast tomography can efficiently image brain tissue at subcellular resolution.
Safe Khan   +15 more
wiley   +1 more source

Small Object Detection Method for Bioimages Based on Improved YOLOv8n Model

open access: yesIntegrative Zoology, EarlyView.
This study proposes a small object detection method for bioimages based on an improved YOLOv8n model. Experimental results demonstrate that the proposed approach effectively enhances detection precision, recall, and mAP50, offering a novel solution for the technical challenges in biological microscopy research.
Xiaoyu Li   +7 more
wiley   +1 more source

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