Results 61 to 70 of about 177,865 (310)

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

Advanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk, Eylul Gulsen Yilmaz, Yusuf Aslan, Emre Ece, Özgecan Erdem, Murat Alp Gungen, Bengi Özgün Öztürk, Fatih Inci   +7 more
wiley   +1 more source

Combination of 3D and 2D Small and Wide Angle X‐Ray Scattering Imaging Reveals Diminished Bone Quality in the Superior Human Femoral Neck Cortex

Advanced Materials, EarlyView.
Combined 2D and 3D X‐ray scattering imaging is used to analyse nanostructural properties in the inferior and superior cortex of 78 human femoral necks from 44 donors. The methodology allows for increased interpretation of nanostructure in a statistically relevant dataset, revealing nanostructural differences in anatomical locations critical to clinical
Torne Tänzer, Tatiana Kochetkova, Arthur Baroni, Mathieu Simon, Mads Carlsen, Santiago Fernandez Bordin, Manuel Guizar‐Sicairos, Philippe Zysset, Marianne Liebi   +8 more
wiley   +1 more source

Relation of mitochondrial phospholipase A activity to mitochondrial swelling

Journal of Lipid Research, 1969
Assays of mitochondrial phospholipase A activity and mitochondrial swelling demonstrated that the phospholipase A activity is related to the swelling under the experimental conditions used.
Moseley Waite, L.L.M. van Deenen, T.J.C. Ruigrok, P.F. Elbers   +3 more
doaj   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

Hyperactivity is linked to elevated cortisol levels: comprehensive behavioral analysis in the prenatal valproic acid-induced marmoset model of autism

Translational Psychiatry
Hyperactivity is frequently observed in individuals with autism spectrum disorder (ASD) and significantly affects various aspects of life. This underscores the critical need for effective intervention methods tailored to the needs of individuals with ASD.
Madoka Nakamura, Toru Nakamura, Akiko Nakagami, Keiko Nakagaki, Nobuyuki Kawai, Noritaka Ichinohe   +5 more
doaj   +1 more source

Selection and isolation of bacterium with probiotic potential from the Amazon ornamental fish Hypancistrus sp. (Siluriformes, Loricariidae)

Boletim do Instituto de Pesca, 2023
The aim of this study was to select autochthonous bacteria with probiotic potential from the gastrointestinal tract of King Tiger Pleco (Hypancistrus sp.) for future applications in captive production.
Ryuller Gama Abreu Reis, Higo Andrade Abe, Natalino da Costa Sousa, Rossineide Martins da Rocha   +3 more
doaj  

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Three in one: evolution of viviparity, coenocytic placenta and polyembryony in cyclostome bryozoans

BMC Ecology and Evolution, 2021
Background Placentation has evolved multiple times among both chordates and invertebrates. Although they are structurally less complex, invertebrate placentae are much more diverse in their origin, development and position.
U. A. Nekliudova, T. F. Schwaha, O. N. Kotenko, D. Gruber, N. Cyran, A. N. Ostrovsky   +5 more
doaj   +1 more source

The Effect of the Synergistic Combination of Vitamin D and Doxorubicin on the MCF-7 Line Breast Cancer Cells

Biology and Life Sciences Forum, 2023
Breast cancer is the most prevalent cancer in the female population. The prolonged action of estrogen may affect tumor proliferation. Additionally, a fat-rich diet may have various effects on cancer proliferation, depending on the type of fat. Vitamin D,
Kamila Sobczak, Agnieszka Mlicka, Paweł Niewiadomski, Oliwia Abramczyk, Wioletta Zielińska, Marta Hałas-Wiśniewska, Magdalena Izdebska   +6 more
doaj   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source