Results 41 to 50 of about 13,487,102 (356)

Protective effects of Zingiber cassumunar Roxb. extract against UVB‐induced oxidative stress in Wistar albino rats (Rattus novergicus Berkenhout, 1769)

Indonesian Journal of Biotechnology
Protecting the skin from the effects of UVB radiation using natural products is crucial in the cosmeceutical industry. This study aims to investigate the protective effects of Bangle (Zingiber cassumunar Roxb.) against UVB‐induced skin damage in Wistar ...
Dian Ayuning Tyas, Nastiti Wijayanti, Tri Rini Nuringtyas, Subagus Wahyuono   +3 more
doaj   +1 more source

Effects of Ultraviolet-B Radiation in Plant Physiology

Agriculture, 2021
Over the past few decades, anthropogenic activities contributed to the depletion of the ozone layer, which increased the levels of solar ultraviolet-B (UV-B) radiation reaching the Earth`s surface. Generally, UV-B is harmful to all living organisms.
Nassour Rana, Ayash Abdulkarim
doaj   +1 more source

Narrow-Band 311 nm Ultraviolet-B Radiation Evokes Different Antioxidant Responses from Broad-Band Ultraviolet

Plants, 2021
Supplemental narrow-band 311 nm UV-B radiation was applied in order to study the effect of this specific wavelength on tobacco as a model plant. UV-B at photon fluxes varying between 2.9 and 9.9 μmol m−2 s−1 was applied to supplement 150 μmol m−2 s−1 ...
Arnold Rácz, Éva Hideg
doaj   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Ultraviolet Spectropolarimetry: on the origin of rapidly rotating B stars

Astrophysics and Space Science, 2022
38 pages, 16 figures, 1 table, topical collection in Astrophysics and Space Science: UV Spectropolarimetry for Stellar, Interstellar, and Exoplanetary Astrophysics with ...
C. E. Jones, J. Labadie-Bartz, D. V. Cotton, Y. Nazé, G. J. Peters, D. J. Hillier, C. Neiner, N. D. Richardson, J. L. Hoffman, A. C. Carciofi, J. P. Wisniewski, K. G. Gayley, M. W. Suffak, R. Ignace, P. A. Scowen   +14 more
openaire   +4 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Comparison of Ultraviolet A/B and C Irradiation for Exosome Secretion Enhancement in HEK 293T Cell

Engineering Proceedings
Exosomes, extracellular vesicles known for their stability, low immunogenicity, and excellent tissue penetration, are employed as delivery vehicles. These exosomes can traverse the tumor barrier and deliver therapeutic agents directly into pancreatic ...
Ching-Chih Chan, Pohao Lin, Yi Xian, Ruey-Hwang Chou, Yi-Jui Liu   +4 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source