Results 61 to 70 of about 522,116 (371)

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

A Study of the Near-Ultraviolet Spectrum of Vega

, 2005
UV, optical, and near-IR spectra of Vega have been combined to test our understanding of stellar atmospheric opacities, and to examine the possibility of constraining chemical abundances from low-resolution UV fluxes.
Alejandro Garcia‐Gil, Allende Prieto C., Alonso A., Bell R. A., Bertelli G., Carlos Allende Prieto, Castelli F., Castelli F., Cunto W., Grevesse N., Holweger H., Hubeny I., Ilijic S., Ivan Hubeny, Kurucz R. L., Moon T. T., Nelder J. A., Perez Hernandez F., Ramon J. Garcia Lopez, Sturenburg S., Terez G. A., Vasil’Yev I. A.   +21 more
core   +2 more sources

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

Development and validation of RP-LC and uv spectrophotometric methods to assay bromopride in oral and injectable solutions

Química Nova, 2010
A reversed-phase liquid chromatographic (LC) and ultraviolet (UV) spectrophotometric methods were developed and validated for the assay of bromopride in oral and injectable solutions. The methods were validated according to ICH guideline.
Márcia Camponogara Fontana, Felipe Kellermann Hurtado, Micheli Wrasse, Aline Augusti Boligon, Tarcieli Pozzebon Venturini, Clarice Madalena Bueno Rolim, Ruy Carlos Ruver Beck   +6 more
doaj   +1 more source

Synthesis of silver nanoparticles using plant extracts from Erythrina abyssinica aerial parts and assessment of their anti-bacterial and anti-oxidant activities

Results in Chemistry, 2022
In the present study, silver nanoparticles were synthesized using Erythrina abyssinica aerial parts as both reducing and capping agents. Three extracts were obtained from the plant using methanol, acetone and water.
Netai Mukaratirwa-Muchanyereyi, Cecilia Gusha, Munyaradzi Mujuru, Upenyu Guyo, Stephen Nyoni   +4 more
doaj   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Improvement of the Method for Determining Total Nitrogen in Water Quality Using Alkaline Potassium Persulfate Ultraviolet Spectrophotometry

Yankuang ceshi
Alkaline potassium persulfate (K2S2O8) ultraviolet (UV) spectrophotometry is the routine method to analyze total nitrogen (TN) in water and is important for studying pollutants in water and the geochemical cycling of TN.
Zhenchao LIU, Zhixiong LI, Qianshu LU, Xiaona WANG, Song ZHANG, Yaohua HU   +5 more
doaj   +1 more source